The discovery and development of drugs is high in both cost and risk.  On average it takes between 12 -15 years to bring a drug to market following its conception and can cost in the region of $1.8 billion.  Discovering toxicity issues late in this process can therefore be financially devastating for a company.

Assessment of toxicity early on can reduce this risk, meaning the focus of Pharma has fallen on mass ADMET consideration.  Identifying ADMET issues early can give Pharma the opportunity to increase the likelihood of success, reduce associated costs and minimise the time to market for a drug candidate.

SMi’s 4^th annual ADMET conference aims to bring together experts in the fields of ADME and toxicology to discuss the methods that can be employed in this quest.  With a varied programme, including in vitro ADME, computational methods relating to ADME and in vitro toxicity studies. 

Why should you attend this event?

This conference aims to address a number of issues including:

• In vitro/in vivo ADME
• In silico ADME prediction
• Toxicity prediction methods
• Developing working relationships between medicinal & computational chemists

The key benefits of attending are: 

• Hear specific examples of leading pharma companies’ ADMET techniques
• Develop an understanding of how to save money and valuable time in your pipeline
• Gain a valuable insight in to the tools that can be employed to reduce the time to market for your drug
• Broaden your background in cost-effective approaches to drug design and development

Hear keynote addresses from:

• Andreas Goller, Senior Scientist, Bayer Healthcare

Our expert speaker line-up also includes:

• David Millan, Senior Principal Scientist (Design Leader), Pfizer
• Fabrizio Giordanetto, Associate Principal Scientist, AstraZeneca
• Mette Gulbrandt. Section Head, Novo Nordisk
• Willem Schoonen, Group Leader, In Vitro Toxicology and Toxicogenomics, Section DMPK & Safety, Schering Plough
• Frank Blaney, Formerly Research Manager, GlaxoSmithKline
• Gary Manchee, Head Business Development, Pharmidex
• Professor John Dearden, Emeritus Professor, Liverpool John Moores University
• Mike Waring, Team Leader, Medicinal Chemistry, AstraZeneca

Who should attend?

Delegates at last years event included:

Abbott Laboratories Abcellute ABL BV Apredica AstraZeneca Boehringer Ingelheim GmbH & Co. KG Boehringer Ingelheim Pharma Corning Inc Cyprotex Discovery Ltd Debiopharm Eli Lilly and Company Epix Pharmaceuticals Ltd Frost & Sullivan G E Healthcare Ltd Italfarmaco Spa Johnson & Johnson KBioscience

Merck KGaA Merck Serono Merz Pharmaceuticals GmbH Neuropharma, S.A. Orion Corporation pharma algorithms Rottapharm SpA Sanofi-Aventis Simulations Plus, Inc. Solvay Pharmaceuticals GmbH Sovicell Gmbh SYMYX Technologies UK Takeda Pharmaceuticals Europe Ltd Technology Networks Thermo Fisher scientific Tibotec UCB Pharma SA

Venue details

Crowne Plaza St James London   . 45-51 Buckingham Gate London   SW1E 6AF   Tel: +44 (0) 207 834 6655 Fax: +44 (0) 207 6307   www.london.crowneplaza.com

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The hotel boasts three excellent restaurants. Bistro 51 with British and European cuisine, the Michelin Starred Indian restaurant Quilon serving south coastal Indian food and Bank Westminster with a modern British menu.  A beautiful, award-winning, courtyard garden surrounds the Victorian buildings of the Crowne Plaza London St James - a peaceful oasis in the centre of London.
 
Nearest train stations:
• Victoria Station, 7 minutes’ walk
• Waterloo Station, 10 minutes by car

Underground stations
• St James’s Park, 5 minutes’ walk (District and Circle lines)
• Victoria Station, 7 minutes' walk (Victoria, District and Circle lines)

SMi discounted rates include Continental Breakfast & VAT
£ 205.63 / Standard room / night for single occupancy
£ 229.13 Executive  room / night for single occupancy

Book your accommodation at SMi discounted rates by calling us on +44 (0)870 9090 713, sending a fax to +44 (0)870 9090 714 or emailing hotels@smi-online.co.uk.