| 8.30 |
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Registration & Coffee |
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| 9.00 |
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Chairman's Opening Remarks |
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Victor Turcanu, Lecturer in Paediatric Allergy, King's College London.
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| 9.10 |
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METHOD FOR EXTRACTION, REVERSE TRANSCRIPTION AND PCR APPLICABLE TO SINGLE CELL ANALYSIS |
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Neven Zoric, manager & co- founder, Tataa biocenter.
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| 9.50 |
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MicroRNA EXPRESSION PROFILES IN ACUTE MYELOID LEUKAEMIAS |
- Use of stem-loop real-time PCR to measure the expression of miRNAs in 100 AML patient samples
- Correlation of miRNA expression with cytogenetic features of the AML samples
- Correlation of miRNA expression with gene expression profile of the same set of samples
- Comparison of miRNA measurement by real-time PCR and detection by high-throughput clonal sequencing in a subset of AML patients
Silvana Debernardi, Research Assistant, Institute of Cancer.
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| 10.30 |
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Morning Coffee |
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| 11.00 |
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SCORPIONS REAL-TIME SIGNALING AND ITS APPLICATIONS IN COMPANION DIAGNOSTICS |
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Sabina Patel, Product Development Scientist, DxS Ltd.
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| 11.40 |
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SENSITIVITY, SPEED AND MULTIPLEXING - NEW TECHNOLOGIES IN RT-PCR |
- Technologies to improve the sensitivity of real-time PCR
- Faster cycling PCR strategies
- Multiplex real-time PCR without optimization
Annette Tietze, Senior Global Product Manager qPCR, QIAGEN.
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| 12.20 |
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Networking Lunch |
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| 1.50 |
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GENOMIC INTEGRATION FOR LONG-TERM GENE EXPRESSION USING |
- Magnetic drug targeting to the lungs
- Targeted nanoparticles for aerosol gene delivery
- Using mRNA for pulmonary gene delivery
Carsten Rudolph, Professor, klinikum der Universitat Munchen.
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| 2.30 |
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BIOMARKERS TO CLINIC: A SYSTEM TO BANISH THE CURSE OF TOO MANY GENES AND TOO FEW SAMPLES |
- The BioTrove OpenArrayTM NT Cycler system extends the reach of genomic discovery, validation and quantification processes by means of a unique parallel array format
- Using proven solution-based qPCR chemistries the system delivers outstanding analytical performance with medium throughput, with an ideal sample-feature ratio
- Driving discoveries in gene signatures, quantitative trait loci, bridging the gaps in validation in toxicogenomics and pharmacogenomics towards translational medicine
Jim White, Europen Technical Manager, BioTrove Inc.
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| 3.10 |
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Afternoon Tea |
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| 3.40 |
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qPCR FOR IN VIVO QUANTIFICATION OF OLIGONUCLEOTIDE INDUCED ONCOGENE INHIBITION |
- The selected oligonucleotides allow both the in vivo inhibition of tumour growth and down regulation of the fusion oncogene at the mRNA level
- RT PCR allows the identification in gel electrophoresis of the targeted mRNA
- qPCR is therefore essential for the in vitro selection of the best oligonucleotides and for the confirmation that their antitumor activity in vivo is related to the targeted oncogene inhibition
Claude Paul Malvy, Director, Universite Paris Sud.
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| 4.20 |
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Chairman's Closing Remarks and Close of Conference |
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