Home
Adaptive Designs for Multi-Armed Trials
2 February 2010
Adaptive Designs for Multi-Armed Trials

About the workshop

The workshop describes the statistical principles for planning and conducting a multi-armed adaptive trial.  This includes an introduction into adaptive designs - what is meant by adaptive?  The focus of this workshop is on confirmatory adaptive designs mainly performed in phase II/III designs where control of Type I error rate is mandatory.  The ways of reaching a test decision, selecting treatment arms, calculating confidence intervals and p-values are described.  Finally, software for performing such analyses is presented and illustrated by examples.

About the host

Gernot Wassmer 

Gernot Wassmer, Professor, Institute for Medical Statistics, Informatics and Epidemiology (IMSIE), University of Cologne

Gernot Wassmer PhD is an Associate Professor for Biostatistics at the Institute of Medical Statistics at the University of Cologne in Germany.  He received his PhD in 1993 at the University of Munich, Germany.  From 1993-2000, he was a Research Fellow at the Institute of Statistics at the University of Munich, also at the Institute for Epidemiology, GSF Neuherberg, and at the Institute of Medical Statistics, University of Cologne.  He also works as a statistical consultant for the pharmaceutical industry.  His major research interest is in the field of statistical procedures for group sequential and adaptive plans in clinical trials.

University of Cologne 

 About the organisation

The University of Cologne is a research university at the highest level with more than 250 co-operating instututes and departments.  The Institute for Medical Statistics, Informatics and Epidemiology offers research, teaching services and consultancy with special emphasis on biometrical reserach and its applications in clinical trials.

Workshop agenda

clock

8:30

Registration & Coffee

clock

9:00

Welcome & Introductions

clock

9:10

Background to Adaptive Designs

  • The Combination Testing principle
  • Adaptive seamless designs
  • The Closed Testing principle
  • clock

    9:50

    Statistical Issues

  • Testing procedures for multi-armed designs
  • Designing parameters
  • Comparison of the procedures
  • Overall p-values and confidence intervals
  • clock

    10:30

    Morning Tea

    clock

    10:50

    Practical Performance

  • Software for planning and analysing multi-armed trials
  • Practical examples
  • clock

    11:30

    Discussion session

    clock

    12:00

    Close of Workshop

    Crowne Plaza Hotel - St James

    Buckingham Gate 45/51
    London SW1E 6AF
    United Kingdom

    Crowne Plaza Hotel - St James

    HOTEL BOOKING FORM

    Title

    SubTitle
    speaker image

    Content


    Title


    Description

    Download

    Title


    Description

    Download

    Title


    Description


    Download


    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

    Event Title

    Headline

    Text
    Read More

    I would like to speak at an event

    I would like to attend an event

    I would like to sponsor/exhibit at an event

    SIGN UP OR LOGIN

    Sign up
    Forgotten Password?

    Contact SAE Media Group

    UK Office
    Opening Hours: 9.00 - 17.30 (local time)
    SAE Media Group , Ground Floor, India House, 45 Curlew Street, London, SE1 2ND, United Kingdom
    Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
    Website: http://www.smgconferences.com Email: events@saemediagroup.com
    Registered in England - SMi Group Ltd trading as SAE Media Group




    Forgotten Password

    Please enter the email address you registered with. We will email you a new password.

    Thank you for visiting our event

    If you would like to receive further information about our events, please fill out the information below.

    By ticking above you are consenting to receive information by email from SAE Media Group.
    Full details of our privacy policy can be found here https://www.smgconferences.com/privacy-legals/privacy-policy/.
    Should you wish to update your contact preferences at any time you can contact us at data@smgconferences.com.
    Should you wish to be removed from any future mailing lists please click on the following link http://www.smgconferences.com/opt-out

    Fill in your details to download the brochure

    By submitting this form you agree to our privacy policy and consent to receiving communications, you may opt out at any time.