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ADME for the Medicinal Chemist
5 December 2014
ADME for the Medicinal Chemist

The course gives an overview of the ADME process and covers concepts such as solubility, permeability, Pgp, CYP 450’s, Phase 1 & 2 metabolism, glomerular filtration and enteropathic cycling. It demystifies pharmacokinetic terms such as t1/2, clearance and volume of distribution.

Interactive workshops place heavy emphasis on the use of current medicinal chemistry literature to solve recurrent ADME issues. Using the ‘succeed through the literature approach’ participants will distil out working solutions to issues such as solubility, oral absorption, CNS penetration and duration of action.

Who should attend

Recommended to medicinal chemists who have recently joined the pharmaceutical industry and more experienced medicinal chemists (up to 5 years in industry) who wish to pull together a range of notions they have picked up in the course of their projects. It is also suited to students & academics who have an interest in current issues in the drug discovery process.
 

Masterclass agenda

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8:30

Registration & Coffee

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9:00

Aims of Masterclass

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9:30

Lecture 1. Digestion

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10:10

Round table: Routes of administration

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10:30

Lecture 2. Solubility

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11:10

Morning Coffee

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11:30

Lecture 2. Solubility & Workshop

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12:15

Networking Lunch

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13:15

Lecture 3. Permeability & P-gp

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14:15

Lecture 4. Liver Metabolism

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15:15

Afternoon Tea

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15:30

Lecture 5. Pharmacokinetics

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16:00

What have we learned?

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16:30

End of Masterclass

MSE Meeting Rooms

103a Oxford Street
London
United Kingdom

MSE Meeting Rooms

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

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