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The workshop will focus on membrane transporters and their application in drug discovery and development. The workshop will introduce the clinically relevant uptake and efflux transporters and their role in drug pharmacokinetics and the important concept of transporter mediated clinical drug-drug interactions. The attendee will also learn about the various transporter in vitro and in vivo tools and prediction models as well as strategies.

The workshop will serve as a nice introductory course to Pharmaceutical scientists to gain knowledge of drug transporters as well as be a refresher to experienced scientists in the field of drug development and research. The workshop will be a nice platform to discuss any case-studies or strategies related to the transporter science.

DMPK
Computational
Principle scientist
Drug metabolism
ADME Toxicologist
Research fellow
Computational scientist
PK/PD modeling
Toxicologist
Anatomy
Stem cell

Aptuit (Verona) S.r.l; Astex Pharmaceuticals; AstraZeneca; Boehringer Ingelheim Pharma GmbH & Co. KG; Cancer Research Technology; Corning Life Sciences; Domainex; Galapagos NV; Genentech, Inc.; GSK; GW Pharmaceuticals plc; Imperial College; Imperial College London; Institute of Cancer Research; inVentiv Health Clinical; Johnson & Johnson; Johnson&Johnson Pharmaceutical R&D; LHASA Ltd; Novartis Institutes for BioMedical Research; Orion Corporation Orion Pharma; Oxagen Limited; Oxagen Ltd; Polyphor Ltd; Redx Pharma; Roche Pharmaceuticals; Sigma Aldrich; Sigma Aldrich Co Ltd; Sussex University; Takeda Cambridge Limited (TCB); The Research Network Ltd; U S Foodservice Baltimore Maryland; Ucb Pharma; University Of Basel; University Of Campinas; University Of East London; University Of Edinburgh; University Of Surrey; Vertex Pharmaceuticals; Xenotech; York Bioanalytical Solutions Limited;

Workshop LEADER

keynote-img

Kunal Taskar

Senior Investigator & Associate Fellow, GSK

Kunal Taskar, Ph.D., is currently working as an Associate GSK Fellow at GlaxoSmithKline, U.K. in Mechanistic Safety and Disposition, IVIVT R&D department. He is the transporter expert at the GSK UK site and consults on drug transporter related project questions from early drug discovery to post-marketing drug development. His past experience includes working as a drug transporter expert in the DMPK Pharmaceutical Candidate Optimization department at Biocon Bristol-Myers Squibb Research and Development. Kunal completed his doctorate and postdoctoral research at Texas Tech University Health Sciences department, USA, in Quentin Smith’s lab with research focused on drug delivery to central nervous system and role of transporters in drug delivery across the blood-brain barrier (BBB).

Kunal’s experience and research focus include: drug-drug interaction predictions and mechanistic understanding of the clinically occurring drug–drug interactions; transporter mediated drug delivery and intracellular drug concentrations, especially the role of uptake (OATPs, OATS, OCTs, MATEs, PEPTs, other SLCs) and efflux (P-gp, BCRP, MRPs, other ABCs) transporters in drug pharmacokinetics-pharmacodynamics and disease and toxicology; novel transporters and role in drug disposition (research on critical role of novel transporters at the BBB); improvising current transporter assays and models for drug transporter studies and clinical predictions; and use of endogenous probes for drug mediated transporter modulations.

Kunal is a member of American Association of Pharmaceutical Scientists (AAPS) and the International Brain Barriers Society. Kunal is also a member of the Predictive Safety Testing Consortium Hepatox working group focused on bile salt export pump transporter. He received the 2014 AAPS Pharmaceutical Research Meritorious Manuscript Award for a manuscript that was published in the same journal in 2012. He served as chair of the AAPS Texas Tech University student chapter in 2011, and chaired the Gordon-Kenan Research Seminar on Barriers of the CNS in 2010.

GSK

GlaxoSmithKline is a science-led global healthcare company on a mission: GSK wants to help people do more, feel better, live longer. Today there are still millions of people without access to basic healthcare, thousands of diseases without adequate treatments and millions more people who suffer from everyday ailments. At GSK we want to change this. GSK has three world-leading businesses that research, develop and manufacture innovative pharmaceutical medicines, vaccines and consumer healthcare products. GSK is committed to widening access to its products, so more people can benefit, no matter where they live in the world or what they can afford to pay.

Workshop programme

8:30 Registration & Coffee

9:00 Opening Remarks

9:10 Session 1 – Introduction to Membrane Transporters

Kunal Taskar

Kunal Taskar, Senior Investigator & Associate Fellow, GSK
View Bio

9:50 Session 2 – Clinically Relevant Drug Transporters

Kunal Taskar

Kunal Taskar, Senior Investigator & Associate Fellow, GSK
View Bio

10:30 Morning Coffee

11:00 Session 3 – How to study the Drug Transporters and why to study Drug Transporters

Kunal Taskar

Kunal Taskar, Senior Investigator & Associate Fellow, GSK
View Bio

11:40 Session 4 – Regulatory Recommendations and when to study the Drug Transporters

Kunal Taskar

Kunal Taskar, Senior Investigator & Associate Fellow, GSK
View Bio

12:20 Closing Remarks

12:30 Close of Workshop

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Holiday Inn Kensington Forum

97 Cromwell Road
London SW7 4DN
United Kingdom

Holiday Inn Kensington Forum

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

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There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

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The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

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