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SMi is proud to announce the return of their 3rd annual Peptides event to London in 2016!



In recent years, therapeutic peptides have been developed for the treatment of several diseases such as cancer, metabolic disorders, nervous system disorders and gastrointestinal disorders, among others. Further research has been done to develop a rich pipeline of novel peptides as a result of their efficacy treating a huge array of conditions, and the global peptide therapeutics market is expected to reach a value of US$23.7B by 2020*

SMi’s 3rd annual Peptides event provides the perfect platform to discuss the latest innovations and development in the peptides industry and explore a number of pressing issues such as the use of Cell Penetrating Peptides (CPP), the challenges involved with oral peptides and many more.

*http://www.prnewswire.com/news-releases/peptide-therapeutics-market-will-rise-at-a-moderate-28-cagr-to-touch-us237-bn-by-2020-transparency-market-research-566039311.html



 


 

Hear from and meet with the key innovators in peptides research,
technologies and peptide therapeutics.

Discover collaborative solutions to peptides research and
technology challenges.

Discuss the latest innovations in peptide therapeutics, including utilising peptides in the clinic and
developments in peptide drug delivery systems
 

 • Head of Formulation
• Head of Peptide Chemistry
• Vice President, Peptides
• Vice President, Diabetes Protein and Peptide Chemistry
• Head of small molecules
• Formulation Scientist
• Global Head of Protein Engineering
• Lab Head of Early Development

 

Amcure; Bachem; Bicycle Therapeutics Limited; Bracco Imaging spa; CHEMI; Complix NV; CUNY-Hunter College; Ensemble Therapeutics; Ferring; GSK; Haemostatix Ltd; Ipsen Research Laboratories; Kings College London; Lonza Group Ltd; Med Immune; Medical University of Vienna; MedImmune; MHRA; Nexigen GmbH; Novo Nordisk; Pfizer; Pfizer Laboratories Ltd; Polypeptide Laboratories A B; Proxima Concepts Ltd; RAPID Pharmaceuticals; Selcia Ltd; Sunpharma; Tepnel Pharma Services; The University of Reading; UCB Pharma Limited; UCD School of Biomolecular and Biomedical Science Conway Institute University College Dublin; UCL Institute of Child Health; University; University College London Medical School; University Of Kent; University Of Southampton; University of Warwick; Whiteknights, Reading;

Conference programme

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Lutz Jermutus

Lutz Jermutus, Senior Director, R&D, MedImmune

9:10 MEDI0382, a novel GLP1/glucagon co-agonist, as a promising therapeutic lead for the treatment of Type 2 diabetes and obesity

Lutz Jermutus

Lutz Jermutus, Senior Director, R&D, MedImmune

• Pre-clinical summary
• Clinical summary
• Mechanism of action studies
 

9:50 Purification of synthetic peptides by reversed phase chromatography

Mathias  Schaffrath

Mathias Schaffrath, Group Head Chromatography, Sanofi

• High throughput purifi cation by automation
• Mass triggered fractioning
• High quality and good recovery of the fi nal product

10:30 Morning Coffee

10:50 Peptide materials for the targeted and responsive delivery of therapeutics

11:30 Assessing immunogenicity in peptide development

Gary  Bembridge

Gary Bembridge, Director of Scientific Affairs Immunology, Abzena

• T-cell help as a risk factor in the development of
anti-drug antibodies
• Immunogenicity of peptides data updates
• Deimmunisation of naturally immunogenic non-human protein therapeutics

12:10 Networking Lunch

13:10 Live learning lab: Strategy for successful GMP peptide development, scale-up and manufacturing

Vincent Bille

Vincent Bille, Founder & Owner, Marble Pharma Consult, sprl

This interactive session will provide live insights related
to process and analytical development, management
of external supply operations. As well as demonstrate a life
cycle approach to manufacturing of peptide APIs including
process and regulatory dimensions.


• Challenges and decision points from early process
development
• Scaling-up: strategy and cost optimisation
• Validation and regulatory requirements
• Contract manufacturing and outsourcing management

14:10 Oral peptide delivery technology landscape

Leila Narimen Beniddir

Leila Narimen Beniddir, Study Manager/Scientist- Novel Drug Delivery Technologies, Ipsen

• Current status
• Particular considerations or oral peptide delivery
• Approaches and strategies for oral peptide delivery

14:50 Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis models

Ashok Bhandari

Ashok Bhandari, VP, Chemistry, Protagonist Therapeutics

• Discovery of novel peptides antagonist for human IL-23
receptor that are
• Orally stable, GI restricted
• Selective
• Effi cacious in rat TNBS colitis model

15:30 Afternoon Tea

15:50 Using Cupid, a novel cell penetrating peptide, to carry GFP into cells

Jonathan  Ryves

Jonathan Ryves, Director, Cupid Peptides

• Advances in Cupid CPP technology
• Applications in stem cell research
• Looking to the future

16:30 Design of the theranostic CXCR4 ligand Pentixafor and its application in man

Oliver Demmer

Oliver Demmer, Innovation Consultant, Innovation Centre Denmark, Ministry Of Foreign Affairs

• Design of Pentixafor: N-methylated, cyclic peptides,
dimers and peptoids
• Optimisation of N-methylation/alkylation procedures
and other peptide modifi cations
• Effi cient on-resin strategies for the synthesis of branched
and modifi ed peptides
• PET imaging in man for cancer diagnosis using Pentixafor

17:10 Chairman’s Closing Remarks and Close of Day One

Lutz Jermutus

Lutz Jermutus, Senior Director, R&D, MedImmune

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Dan Teufel

Dan Teufel, Head of Chemistry, Bicycle Therapeutics Limited

9:10 New synthetic anti tuberculosis cyclohexylgriselimycin, more than 50 years after the isolation of the natural griselimycin

• Case study in peptide chemistry
• Modern day optimisation of the natural compound
Griselimycin (GM)
• Novel mode of action and anti-TB properties

Evelyne Fontaine

Evelyne Fontaine, Scientist, Sanofi-Aventis

9:50 CMC case study: Process development, commercial manufacturing and quality control for generic peptide APIs

Daniel Samson

Daniel Samson, Director API Manufacturing, Bachem
View Bio

• Chemical process development, scale-up and large
scale manufacturing of the two generic peptide APIs
Atosiban and Lanreotide
• Analytical control strategy (starting material quality, inprocess
controls, API specifications)
• Comparison of process parameters and drug
substance quality attributes from process performance
qualification and commercial manufacturing

10:30 Morning Coffee

10:50 Development of cytotoxic bicyclic peptide drug conjugates and applications in molecular targeted cancer therapy

• Peptide drug development
• Toxin Conjugate development
• Radio-nuclide conjugates, biodistribution
• Formulation (possibly), physchem etc
• In vitro/vivo results

Dan Teufel

Dan Teufel, Head of Chemistry, Bicycle Therapeutics Limited

11:30 Developing a peptide coagulant and formulation to treat traumatic bleeding

Renata Zbozien

Renata Zbozien, Senior Scientist, Haemostatix Ltd

• Unmet needs in the control of traumatic bleeding
• Design of peptide coagulant and formulation
• Progress to date

12:10 Networking Lunch

13:10 Enhanced drug delivery with Veltis® engineered albumins

Joanna Hay

Joanna Hay, Science Manager, Albumedix

• Short circulatory half-life represents a major obstacle for
many peptide-based therapeutics.
• This can be signifi cantly improved by conjugation or
fusion to albumin, due to increased size and recycling
via the neonatal Fc receptor (FcRn).
• The increased FcRn affi nity of the Veltis® engineered
albumins translates to more than doubling of the already
long half-life of native sequence albumin.
• We will describe rationally engineered albumins and

13:50 Using Cyclotides for oral delivery of biotherapeutics.

Bill Eldridge

Bill Eldridge, CSO, Cyclogenix

• Using Cyclotides for oral delivery of biotherapeutics.
• Bispecific Cyclotides as a new class of Immuno-oncology agents.
 

14:30 Afternoon Tea

14:50 Strategies for peptide-based vaccines development for antiviral diseases

Elisabetta Bianchi

Elisabetta Bianchi, Head of Peptide Chemistry , IRBM Science Park

• Identification of potentially protective epitopes
• Design and conjugation of conformationally constrained epitopes
• Strategies to enhance immunogenicity

15:30 Vaccination via the oral route

Roger New

Roger New, Director, R&D, Proxima Concepts Ltd

• Strategies for delivery to Peyer’s Patches
• Deployment of sub-unit vaccines
• Success in challenge models

16:10 Chairman’s Closing Remarks and Close of Day Two

Dan Teufel

Dan Teufel, Head of Chemistry, Bicycle Therapeutics Limited

+

FEATURED SPEAKERS

Dan Teufel

Dan Teufel

Head of Chemistry, Bicycle Therapeutics Limited
Daniel Samson

Daniel Samson

Director API Manufacturing, Bachem
Evelyne Fontaine

Evelyne Fontaine

Scientist, Sanofi-Aventis
Leila Narimen Beniddir

Leila Narimen Beniddir

Study Manager/Scientist- Novel Drug Delivery Technologies, Ipsen
Lutz Jermutus

Lutz Jermutus

Senior Director, R&D, MedImmune

Ashok Bhandari

VP, Chemistry, Protagonist Therapeutics
Ashok Bhandari

Bill Eldridge

CSO, Cyclogenix
Bill Eldridge

Dan Teufel

Head of Chemistry, Bicycle Therapeutics Limited
Dan Teufel

Daniel Samson

Director API Manufacturing, Bachem
Daniel Samson

After obtaining his PhD in organic chemistry Daniel joined Bachem's peptide manufacturing headquarters in Switzerland in 2007. As a team leader he has been responsible for the synthesis of peptides and small proteins. From 2009 to 2011 he held a lab head position focusing on process optimization, technology transfer and scale-up of synthetic peptide manufacturing procedures. In 2010 Daniel joined Bachem in the United Kingdom temporarily focusing on non-GMP custom syntheses of peptides. From the beginning of 2012 he has been leading Bachem’s cGMP API manufacturing groups back in Switzerland applying large scale SPPS and preparative HPLC. Science 2015 he is a Senior Director and has responsibility for all peptide API manufacturing aspects within Bachem AG.

Elisabetta Bianchi

Head of Peptide Chemistry , IRBM Science Park
Elisabetta Bianchi

Evelyne Fontaine

Scientist, Sanofi-Aventis
Evelyne Fontaine

Gary Bembridge

Director of Scientific Affairs Immunology, Abzena
Gary  Bembridge

Joanna Hay

Science Manager, Albumedix
Joanna Hay

Jonathan Ryves

Director, Cupid Peptides
Jonathan  Ryves

Leila Narimen Beniddir

Study Manager/Scientist- Novel Drug Delivery Technologies, Ipsen
Leila Narimen Beniddir

Lutz Jermutus

Senior Director, R&D, MedImmune
Lutz Jermutus

Mathias Schaffrath

Group Head Chromatography, Sanofi
Mathias  Schaffrath

Oliver Demmer

Innovation Consultant, Innovation Centre Denmark, Ministry Of Foreign Affairs
Oliver Demmer

Renata Zbozien

Senior Scientist, Haemostatix Ltd
Renata Zbozien

Roger New

Director, R&D, Proxima Concepts Ltd
Roger New

Vincent Bille

Founder & Owner, Marble Pharma Consult, sprl
Vincent Bille

Sponsors and Exhibitors

Official Media Partner

Official Publication

Supporters

Workshops

Cupid Cell Penetrating Peptides – A Powerful New Tool
Workshop

Cupid Cell Penetrating Peptides – A Powerful New Tool

Holiday Inn Kensington Forum
5th July 2016
London, United Kingdom

VENUE

Holiday Inn Kensington Forum

97 Cromwell Road , London, United Kingdom

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

Preliminary list of attendees - 2016

Download

Interview with Renata Zbozien, VP Research, Haemostatix

Download

Sponsors and Exhibitors


Abzena

Sponsors and Exhibitors
http://www.abzena.com

Abzena offers a suite of complementary services and technologies. Its range of technologies include immunogenicity assessment, antibody drug conjugation, protein engineering, PEGylation, cell line development , GMP manufacturing and a range of bespoke assays to enables the development of better biopharmaceuticals which will have a greater chance of reaching the market.


Bachem

Sponsors and Exhibitors
http://www.bachem.com

Bachem provides comprehensive services to the pharma and biotech industries. It specializes in the development of innovative, efficient manufacturing processes and the reliable production of peptide-based APIs. The group has a global reach with more experience and know-how than any other company in the industry. Bachem. Pioneering Partner for Peptides

Media Partners


WCA Pharma

Official Media Partner
http://www.wcapharma.com

The Members within WCA Pharma all have dedicated personnel fully conversant in the GDP guidelines required for the special handling of Pharmaceutical products. All have the attention to detail required that has seen them become established and recognized by the leading Pharma Industries throughout the world. From Clinical trials, Biotech, Plasma, Laboratory, Health Care, Chilled, Frozen, Controlled Ambient, Packaging, Air, Ocean and Land, you have all Pharmaceutical clusters contained within one exclusive network. Our members are able to pass on their knowledge to clients and use their skills, trust and experience in ensuring all products arrive on time and in the perfect condition. Making sure products are shipped via the correct method, temperature, atmosphere and under controlled conditions ensures these valuable shipments have the care and attention whilst being handled that they deserve.


The Pharma Letter

Official Media Partner
http://www.thepharmaletter.com/

The Pharma Letter provides subscribers with daily, up-to-date news, business intelligence, comment and analysis for the pharmaceutical, biotechnology and generics sectors of the health care industry, backed by a team of respected writers with many years of experience in the field.


BioChem Adda

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ecancer

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Media Partners


International Journal of Healthcare Technology and Management

Official Publication
http://www.inderscience.com/ijhtm

IJHTM is a series emerging from the International Journal of Technology Management. It provides an international forum and refereed authoritative sources of information in the fields of the economics and management of technology in healthcare.


International Journal of Computational Biology and Drug Design

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IJCBDD, an International Society of Intelligent Biological Medicine official journal, bridges the gap between two very important, complementary disciplines, computational biology and drug design. Through advances in high-throughput genome sequencing and digital imaging technologies, biocomputing, drug design and medical research have unfolded new, predictive sciences such as genomics, proteomics, lipidomics, metabolomics, cytomics and pharmaconomics. These promote new computational, statistical and biomedical approaches to drug design/development, besides unleashing the potential of significantly more accurate, effective personalised diagnosis, therapeutics and patient care.


International Journal of Biotechnology

Official Publication
http://www.inderscience.com/ijbt

IJBT provides an international forum and refereed authoritative source of information in the field of Biotechnology and Biotechnics, with emphasis on management and economics, as well as the political and social issues. It aims to disseminate knowledge, provide a learned reference in the field, and establish channels of communication between academic and research experts, policy makers and executives in industry, commerce and investment institutions.


Int. J. of Immunological Studies

Official Publication
http://www.inderscience.com/ijis

IJIS publishes a broad range of papers on all aspects of immunology from scientists in academic and non-academic organisations as well as business and government worldwide. IJIS is the flagship journal of the Frontiers in Immunology Research Network.


International Journal of Biomedical Engineering and Technology

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http://www.inderscience.com/ijbet

IJBET addresses cutting-edge research in the multi-disciplinary area of biomedical engineering and technology. Medical science incorporates scientific/technological advances combining to produce more accurate diagnoses, effective treatments with fewer side effects, and improved ability to prevent disease and provide superior-quality healthcare. A key field here is biomedical engineering/technology, offering a synthesis of physical, chemical, mathematical and computational sciences combined with engineering principles to enhance R&D in biology, medicine, behaviour, and health. IJBET includes the Asia-Pacific Chapter in Biomedical Wireless Technology (APC-BWT).

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Biocompare

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British Pharmacological Society

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The British Pharmacological Society (BPS) is the primary UK learned society concerned with research into drugs and the way they work. Our members work in academia, industry, regulatory agencies and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects. Clinical pharmacology is the medical speciality dedicated to promoting safe and effective use of medicines for patient benefit. Clinical pharmacologists work as consultants in the NHS and many hold prominent positions in UK Universities.


Bentham Science

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Farmavita

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PMR

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Technology Networks

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Founded in 2000, Technology Networks is established as the leading news provider for life science and drug discovery professionals. In addition, we provide unique content including webcasts, videos, application notes and posters from recent conferences. Our portfolio now includes around 30 focussed scientific communities, all of which are accessible free of charge within TechnologyNetworks.com


Mednous

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Swiss Biotech Association

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Drug Discovery Today

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pharmaphorum

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AntibodyChain

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The complete and transparent marketplace for your research antibodies, kits, proteins and small molecules. The sophisticated search engine, with more than 800.000 products, transparency in suppliers, easy comparison, the one stop shop for your research antibodies in combination with interesting news and events plus a CMO exchange makes us a full service partner for you.


Absave

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Pharmalicensing

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Drug Discovery World

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Gate2Biotech

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Antibodies Online

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Holiday Inn Kensington Forum

97 Cromwell Road
London SW7 4DN
United Kingdom

Holiday Inn Kensington Forum

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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Contact SMi GROUP LTD

UK Office
Opening Hours: 9.00 - 17.30 (local time)
SMi Group Ltd, 1 Westminster Bridge Road, London, SE1 7XW, United Kingdom
Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
Website: http://www.smi-online.co.uk Email: events@smi-online.co.uk
Registered in England No: 3779287 VAT No: GB 976 2951 71




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