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SUPERBUGS & SUPERDRUGS 2017

2 DAY CONFERENCE: 20TH & 21ST MARCH
2 INTERACTIVE WORKSHOPS: 22ND MARCH (For details visit the ASSOCIATED EVENTS tab)


SMi is proud to present the 2017 19th annual Superbugs & Superdrugs conference, taking place on 20th and 21st March in Central London.
Expanding horizons on the growing threat of anti-microbial resistance for almost two decades, the flagship show in the global Superbugs portfolio of events will once again play host to an international audience of scientific leaders, funding bodies and drug discovery specialists, providing a focal point to push industry collaboration through updates on clinical advancements and investment opportunities.

Each year, around 2 million people are taken ill in the US from antibiotic-resistant bacteria and kills at least 23,000, according to estimates by the Centers for Disease Control and Prevention. The threat is so high that in September 2014 President Barack Obama issued an executive order Combating Antibiotic-Resistant Bacteria. *

The threat is the same in Europe, big pharmaceutical companies are re-entering the space into development of new antibiotics after decades. In January 2016, more than 80 pharmaceutical, biotechnology and diagnostics companies including Roche, Pfizer, Novartis AG and GlaxoSmithKline pledged at the World Economic Forum to fight the threat of antimicrobial resistance.*

The industry’s premier event on antibiotic resistance will provide a perfect platform for its growing "superbugs" community to network, exchange novel solutions and consolidate current strategies. A must attend for both new and seasoned stakeholders involved in AMR and infectious disease.

https://www.fredhutch.org/en/news/center-news/2015/01/combating-superbugs-superdrugs-antibiotics.html
http://www.iol.co.za/business/international/big-pharma-drawn-back-to-antibiotics-2040209

PREVIOUS ATTENDEE TESTIMONIALS FROM SUPERBUGS & SUPERDRUGS 2016

  • “Great meeting to network and have time to discuss face to face. Key questions and issues. Very collaborative open meeting.” – Roche
  • “It was one of the most useful scientific conferences that I have attended” – BARDA
  • “Good mix of problems such as funding and novel opportunities and success stories” – TNO
  • “I enjoyed attending the meeting this year and wanted to thank you for your efforts in organizing it” – UNT Health Science Centre
  • “I like the mix of early stage technologies and also later stage products being presented” – Sempra Pharmaceuticals

WHAT'S ON THE AGENDA FOR 2017?

• The latest developments in antimicrobial peptides
• Ground-breaking innovations in antibacterial chemotherapy
• Comprehensive overview of government funding initiatives
• A showcase on novel approaches to enabling antibacterial activity against Gram-negative pathogens
• Guidance on antibiotic stewardship
• Updates on clinical progress
• New spotlight on animal models in drug discovery
• Hand on training through CPD certified interactive workshops

CEOs, Chiefs, VPs, Directors, Heads, Principals of:
 

Antibacterial
Infectious Disease
R&D
Microbiology

or working in the area of superbugs and superdrugs from pharmaceutical, biotech and research organizations!
 

Conference programme

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Richard Bax

Richard Bax, Senior Partner, TranScrip Partners

9:10 Antibiotics: current situation and the way forward.

Richard Bax

Richard Bax, Senior Partner, TranScrip Partners

Future challenges in antibiotic R&D and regulation?
Do national research strategies make sense.
What is missing?
What is next?
 

9:50 Regulatory perspective on antibacterial drug development

Sumathi Nambiar

Sumathi Nambiar, Director, Division of Anti-Infective, FDA


-Discuss streamlined development programs
-Activities to facilitate antibacterial drug development
-Discuss some remaining challenges in antibacterial drug development    
 

10:30 Morning Coffee

10:50 Repopulating the Antibacterial Pipeline

Christopher Houchens

Christopher Houchens, Branch Chief, Antibacterials Program, BARDA

• What is BARDA?
• Why BARDA is interested in antimicrobial resistance (AMR)
• How BARDA is addressing the issue of AMR
• Forming innovative public-private partnerships to
accelerate clinical product development
• Stimulating innovation in early stage antimicrobial
research and development

11:30 Statistical and design approaches to allow more feasible antibiotic drug development

Aaron Dane

Aaron Dane, Director, Danestat consulting

• A n outline of alternative statistical approaches and study
designs are being considered and actively discussed
with global regulatory agencies
• H ow likely they are to be possible going forward
• D iscussion of which approaches can already be applied
and which require further work before being considered
part of routine practice

12:10 Networking Lunch

13:30 The use of in vivo models for infectious disease research

William Weiss

William Weiss, Director of Pre-Clinical Services, University of North Texas Health Science Center

• Experimental Design of Animal Models
• Bridging the gap – in vitro activity to in vivo effi cacy
• Where to start / What model to use
• What does the data tell us

14:50 Afternoon Tea

15:10 The development of antimicrobial peptides (AMP) as new antibacterial drugs

Deborah O'Neil

Deborah O'Neil, Chief Executive Officer, Novabiotics Ltd

• Exploring AMP as a viable alternative to antibiotics
• Utilising an AMP different mode of action
• Latest developments in antimicrobial peptides

15:50 Short antimicrobial peptides - their potential to treat bacterial MDR infections

Kai Hilpert

Kai Hilpert, Prof Associate Reader in Infection and Immunology , St George's, University of London

• Screening approach and separation of antimicrobial
activity and haemolytic activity
• Their action against MDR strains
• Preventing biofi lms and destroying existing biofi lms
• Immunomodulatory activities

16:30 Novel oligonucleotide antimicrobials against Gram-negative infections

Michael McArthur

Michael McArthur, Chief Scientific Officer, Procarta Biosystems Ltd.

· Rational design of oligonucleotide antimicrobials to target transcription factors
· Identification of a new Gram-negative therapeutic target
· Validation in microbiome and animal models

17:10 Novel approaches to enabling antibacterial activity against Gram-negative pathogens

Aileen  Rubio

Aileen Rubio, Head of Biology, Spero Therapeutics

• Combating Gram negative pathogens require
innovative approaches in addition to the standard small
molecules
• We have identifi ed an outer membrane permeabilizer,
SPR741, that helps otherwise impermeant antibiotics
entry into the Enterobacteriaecaea.
• Improvements in activity can be observed both in vitro
and in vivo when SPR741 is combined with rifampin or
other antibiotics

17:50 Chairman’s Closing Remarks and Close of Day One

Richard Bax

Richard Bax, Senior Partner, TranScrip Partners

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Lloyd Czaplewski

Lloyd Czaplewski, Director, Chemical Biology Ventures

9:10 How the pharmaceutical industry is helping address AMR?

James Anderson

James Anderson, Head of Government Affairs, GSK

· The role of the pharmaceutical industry in combating AMR goes beyond investing in R&D for new antibiotics
· Companies are partnering with healthcare systems globally to help ensure antibiotics are manufactured cleanly, available to patients where needed and used appropriately
· We seek further progress on implementation of new economic models to deliver sustainable solutions for all.
 

9:50 Exploiting DNA topoisomerases as targets for antibacterial chemotherapy

Anthony Maxwell

Anthony Maxwell, Professor, John Innes Centre

• AMR is a serious and growing problem
• DNA topoisomerases (e.g. DNA gyrases) are successful
and well-validated targets for antibiotics
• Fluoroquinolones are highly-successful antibacterial
agents, but resistance is a serious problem
• Approaches to discover new gyrase inhibitors
• Topoisomerases present new opportunities for antibiotic
targeting

10:30 Morning Coffee

10:50 Finding new small molecule antibiotics

David Williams

David Williams, Chief Executive Officer, Discuva

• Fast and effi cient ways to fi nd new antibiotic
chemotypes
• Ways to focus rational chemical optimisation
• Selection of the best clinical candidates
• Management of clinical resistance

11:30 Fighting back against MBL mediated CREs: development of metallo-beta-lactamase inhibitors for use in combination with carbapenems

Martin Everett

Martin Everett, Head of Biology, Antabio

• MBL-mediated CRE are already endemic in many countries
and rapidly spreading world-wide
• Antabio have identifi ed a potent and selective lead series
with excellent drug-like properties
• Lead compounds show broad spectrum potentiation of
meropenem against clinical CRE isolates and demonstrate
effi cacy in animal models of infection

12:10 Networking Lunch

13:30 Microbome-targeted products: Spare vs repair

Jean de Gunzburg

Jean de Gunzburg, CSO, Da Volterra

• Antibiotic-induced dysbiosis and its consequences
• FMT and microbiota-derived products aimed at
C. diffi cile infections
• Pharmacological interventions targeting the gut
microbiome
• Protecting the intestinal microbiome during antibiotic
treatments

14:10 Afternoon Tea

14:30 Anti-infective monoclonal antibodies against multi-drug resistant pathogens

Eszter Nagy

Eszter Nagy, President and CSO, Arsanis Biosciences GmbH

15:10 Discovery of a novel class of antibiotics

Neil Miller

Neil Miller, Chief Scientific Officer, Auspherix Ltd

• Identifi cation of a new class of broad-spectrum
antibacterials
• Antimicrobial profi les (Gram-positive & Gram-negative)
• In-vitro characterisation and mechanistic insights

17:00 Chairman’s Closing Remarks and Close of Day Two

Lloyd Czaplewski

Lloyd Czaplewski, Director, Chemical Biology Ventures

+

FEATURED SPEAKERS

Aileen  Rubio

Aileen Rubio

Head of Biology, Spero Therapeutics
Christopher Houchens

Christopher Houchens

Branch Chief, Antibacterials Program, BARDA
Eszter Nagy

Eszter Nagy

President and CSO, Arsanis Biosciences GmbH
Jean de Gunzburg

Jean de Gunzburg

CSO, Da Volterra
Richard Bax

Richard Bax

Senior Partner, TranScrip Partners

Aaron Dane

Director, Danestat consulting
Aaron Dane

Aileen Rubio

Head of Biology, Spero Therapeutics
Aileen  Rubio

Anthony Maxwell

Professor, John Innes Centre
Anthony Maxwell

Christopher Houchens

Branch Chief, Antibacterials Program, BARDA
Christopher Houchens

David Williams

Chief Executive Officer, Discuva
David Williams

Deborah O'Neil

Chief Executive Officer, Novabiotics Ltd
Deborah O'Neil

Eszter Nagy

President and CSO, Arsanis Biosciences GmbH
Eszter Nagy

James Anderson

Head of Government Affairs, GSK
James Anderson

Jean de Gunzburg

CSO, Da Volterra
Jean de Gunzburg

Kai Hilpert

Prof Associate Reader in Infection and Immunology , St George's, University of London
Kai Hilpert

Lloyd Czaplewski

Director, Chemical Biology Ventures
Lloyd Czaplewski

Martin Everett

Head of Biology, Antabio
Martin Everett

Michael McArthur

Chief Scientific Officer, Procarta Biosystems Ltd.
Michael McArthur

Neil Miller

Chief Scientific Officer, Auspherix Ltd
Neil Miller

Richard Bax

Senior Partner, TranScrip Partners
Richard Bax

Sumathi Nambiar

Director, Division of Anti-Infective, FDA
Sumathi Nambiar

William Weiss

Director of Pre-Clinical Services, University of North Texas Health Science Center
William Weiss

Xavier Duportet

CEO, Eligo Bioscience
Xavier Duportet

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Official Publication

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Workshops

The Use of Animal Models in Pre-Clinical Drug Development
Workshop

The Use of Animal Models in Pre-Clinical Drug Development

Copthorne Tara Hotel
22nd March 2017
London, United Kingdom

Practical Challenges in Developing Novel Antimicrobials
Workshop

Practical Challenges in Developing Novel Antimicrobials

Copthorne Tara Hotel
22nd March 2017
London, United Kingdom

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Copthorne Tara Hotel

Scarsdale Place, Kensington, London, United Kingdom

The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

 

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Copthorne Tara Hotel

Scarsdale Place
Kensington
London W8 5SR
United Kingdom

Copthorne Tara Hotel

The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

 

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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Contact SMi GROUP LTD

UK Office
Opening Hours: 9.00 - 17.30 (local time)
SMi Group Ltd, 1 Westminster Bridge Road, London, SE1 7XW, United Kingdom
Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
Website: http://www.smi-online.co.uk Email: events@smi-online.co.uk
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