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High Throughput Screening of small molecule collections has become the pre-eminent method of Hit Finding/Lead Generation, driven by the use of robotic screening equipment. However, outcome has been quite variable depending on target type and assay: many challenging
targets and functional assays have provided disappointing results. Screening quality has noticeably improved over the years but modalities other than classical small molecules have been underexplored, as well as novel screening technologies that are only now coming to maturity. Furthermore, innovative solutions originating from a range of academic groups and biotechs require new types of collaboration to leverage and integrate these new approaches.

You want to learn about current hit finding/lead generation and how innovative modalities, technologies and business models are deeply modifying the early stage of drug discovery.

Job roles which are directly linked to  hit finding/lead generation.

Workshop LEADER

keynote-img

Eric Valeur

Associate Director, New Modalities & Lead Generation , AstraZeneca

Eric Valeur obtained his PhD from the University
of Edinburgh under supervision of Prof. Mark
Bradley, where he developed a new approach
to fragment microarrays. As postdoctoral
fellow, he then joined the Northern Institute
for Cancer Research in Newcastle working on inhibitors of
MDM2-p53. Subsequently, he led medicinal chemistry teams
in major therapeutics areas fi rst at Merck-Serono in Paris and
then at Novartis in Basel. In particular, he was involved in
the development of challenging non-peptidic proteases
inhibitors within the Expertise Protease Platform. In 2014, he
joined AstraZeneca in Sweden as Associate Director for New
Modalities to drive research within the chemical space at the
interface of small and large molecules. His present research
interests include small molecules, peptides, macrocycles,
oligonucleotides and conjugates thereof.

Workshop programme

8:30 Registration & Coffee

9:00 Opening remarks and introductions

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

9:10 Current hit finding strategies and small molecule collections have clear limitations

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

9:50 New modalities and technologies can address targets intractable with classical approaches

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

10:30 Morning Coffee

11:00 New business models, partnerships, consortia, open innovation, give access to external knowledge and innovative solutions

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

12:20 Outlook: will directed evolution, synthetic biology, microfl uidics, and other novel approaches enable a new lead generation paradigm?

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

12:30 Close of Workshop

Patrick Jimonet

Patrick Jimonet, External innovation for lead generation , Sanofi

Eric Valeur

Eric Valeur, Associate Director, New Modalities & Lead Generation , AstraZeneca

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VENUE

Holiday Inn Kensington Forum

97 Cromwell Road , London, United Kingdom

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

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Holiday Inn Kensington Forum

97 Cromwell Road
London SW7 4DN
United Kingdom

Holiday Inn Kensington Forum

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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UK Office
Opening Hours: 9.00 - 17.30 (local time)
SMi Group Ltd, 1 Westminster Bridge Road, London, SE1 7XW, United Kingdom
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