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The need for functional delivery of RNAi effectors to target
cells is a primary problem that is holding back the field of
RNAi therapeutics. Nanoparticles, molecular conjugates,
and other delivery technologies have their place but are
they really working well enough? If not why not? And if they
do appear to be working, what will it actually take to realise
clinical success? This workshop is designed to help attendees
appreciate the magnitude of the gap that must be bridged
between academic-preclinical studies and the needs of the
pharma industrial for success in RNAi therapeutics

Reasons to attend:

  • Confused about RNAi delivery technologies?
  • Confused how to move from bench to clinic?
  • Intimidated by regulations and regulators?
  • Baffled by target product profi les and integrated
    development plans?

Company CSOs
Technology transfer officers,
Early stage biotech investors,
Personnel from CROs
Clinical SMOs

Workshop programme

8:30 Registration & Coffee

9:00 Session 1: Where are we really with functional RNAi effector delivery?

Andrew Miller

Andrew Miller, Professor of Organic Chemistry & Chemical Biology, Kings College London
View Bio

  • Do RNAi effectors need a delivery system in vivo?
  • What delivery systems are most biocompatible?
  • How effective are delivery systems today?
  • Where should the state of the art be developed?

    9:50 Session 2: Bridging the gap from lab preparation to kg manufacture

    Andrew Miller

    Andrew Miller, Professor of Organic Chemistry & Chemical Biology, Kings College London
    View Bio

  • The importance of cGMP manufacture
  • What are key problems in scale-up manufacture?
  • 10:30 Morning Coffee

    11:00 Session 3: Integrated development plans-nonclinical studies to clinic

    Andrew Miller

    Andrew Miller, Professor of Organic Chemistry & Chemical Biology, Kings College London
    View Bio

  • Developing a target product profile
  • Mapping out an integrated development plan
  • Addressing regulatory issues at all stages of development
  • 11:45 Session 4: Improving on the status quo

    Andrew Miller

    Andrew Miller, Professor of Organic Chemistry & Chemical Biology, Kings College London
    View Bio

  • How close are we to routine RNAi therapeutics?
  • What are critical problems to address going forward?
  • 12:20 Closing Remarks

    Andrew Miller

    Andrew Miller, Professor of Organic Chemistry & Chemical Biology, Kings College London
    View Bio

    12:30 End of workshop


    Copthorne Tara Hotel

    Scarsdale Place
    London W8 5SR
    United Kingdom

    Copthorne Tara Hotel

    The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

    The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.




    speaker image






    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.


    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.


    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.


    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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