SMi is proud to announce the return the 12th annual Asthma & COPD conference 2016 in London!

Respiratory diseases represent an enormous and increasing healthcare and economic burden across Europe and USA.
Over the last few years, significant improvements in the management of asthma and COPD have been made, owing to new drugs, strategies and to the development of the nonpharmacologic treatment of COPD. Nevertheless, there are still many unmet needs in the treatment of these diseases. 

Join us at SMi's 12th annual Asthma & COPD taking place on the 11th - 12th April 2016 in London. This event will explore innovative asthma and COPD drug development programmes, directives and procedures which have been put in place to reduce the enormous suffering from lung disease and its high mortality.



A series of practical case studies, interactive roundtables and panel discussion facilitated by leading industry experts will provide executives with useful tools and best practices to:
• develop vaccination approaches for asthma
• improve inhaled therapies in COPD and development of antivirals
• evaluate the impact of COPD phenotypes on therapy
• explore biomarkers for respiratory drug assessment
• learn about stratified medicine and prevent exacerbation in asthma and COPD

and many more...

• Discuss the recent advances in asthma and COPD management
• Gain insight into the development of antivirals
• Evaluate the impact of COPD phenotypes on therapy
• Review the practice of personalized medicine
• Learn about stratified medicine
• Explore biomarkers for respiratory drug assessment
• Study the identification of new molecular targets
• Analyse developments of vaccination approaches for Asthma


Chief Executives, Chief Scientific Officers, Chief Medical Officers, Vice Presidents, Heads, Directors, Senior Scientist, Principle Scientists, Clinicians, Physicians, Project Leaders, Specialists, and Managers in the following areas:

• Respiratory Physiology & Medicine
• Respiratory Pharmacology
• Regulatory and Medical Affairs
• Inflammatory Disease
• Respiratory, Inflammation and Autoimmunity
• Pulmonary Disease
• Respiratory Therapeutics
• Immunology
• Medical & Inhalation Devices
• In-Vitro Biology
• Biomarker
• Inflammation Discovery
• Preclinical R&D
• Clinical Pharmacology
• Clinical Trials
• Research and Development
• Business Development
• Brand Manager
• Commercial
• Respiratory

3M Health Care; Aerocrine; Aerocrine AB; Amgen; Artimmune S.A.S; Asthma UK; Astrazeneca; AstraZeneca R&D Mölndal; AstraZeneca UK; Bayer Healthcare AG; Bayer Pharma AG; Biopharm Insight; Carclo Technical Plastics Ltd; Chiesi Farmaceutica SPA; Chiesi Group - Chiesi Farmaceutici S.p.A.; Fraunhofer Institut; Fraunhofer ITEM; Genentech, Inc.; Imperial College; Imperial College School of Medicine (N.H.L.I.); Imperial School Of Medicine London; Johnson and Johnson Pharmaceutical Services LLC; Liverpool School of Tropical Medicine; London North West Healthcare NHS Trust; Manchester University; MedImmune; Norwegian Hearth and Lung Patient Organisation; Osakidetza; Oxagen Ltd; Saba University ; SkyePharma AG; Synairgen Ltd; The University of Nottingham; Thermofisher Scientific; Thomson Reuters; University College London; University of Glasgow; University of Lyon; University Of Oxford; University of the Basque Country; Vectura; Verona Pharma; VIAJES ATLANTA, SA; VIVISOL; Zagreb Hospital Care ;

Conference programme

8:30 Registration & Coffee

9:00 Chairman's Opening Remarks

Ewan Walters

Ewan Walters, Medical Director, Teva UK Ltd

9:10 Recent advances in asthma and COPD management

Neil C Thomson

Neil C Thomson, Professor of Respiratory Medicine, University of Glasgow

  • Management of chronic asthma including severe disease
  • Pharmacological treatments for COPD
  • Management of the asthma-COPD overlap syndrome
  • Assessment of potential impact of drugs under development for asthma and COPD
  • 9:50 COPD: Unmet need and challenges in NHS care

    John Hurst

    John Hurst, Senior Clinical Lecturer, Honorary Consultant, University College London


  • Exploring the care needs of patients
  • The challenge of patients' unmet palliative care
  • Ten key challenges, representing unmet need, in NHS Care for COPD
  • 10:30 Morning Coffee

    11:00 Developing and registering new inhalers to deliver clinical benefits in asthma

    Ewan Walters

    Ewan Walters, Medical Director, Teva UK Ltd

  • Approval process for inhalers in asthma
  • Developing a new inhaler – delivering incremental improvements 
  • Real world data to assess performance for patients and HCPs of new inhalers
  • Characteristics of a new inhaler to provide benefit 
  • Assessment of training procedures in both HCP (doctors and nurses) and patients 
  • Clinical studies in real world and role of observational studies in clinical practice 
  • 11:40 Development challenges for Generic Inhalation Products for EU and US markets

    Nayna  Govind

    Nayna Govind, Director for the development of generic inhalation products , Dr Reddys Laboratories

  • Formulation and device considerations
  • In-vitro bioequivalence
  • EU & US regulatory requirements


  • 12:20 Networking Lunch

    13:30 Formulation and process challenges in the development of inhaled products

    Frank Thielmann

    Frank Thielmann, Operational Lead, Inhalation New Solids, Novartis Pharma AG

  • Device and formulation systems and their selection
  • Properties of drug substance and product and impact on in-vitro/ vivo performance
  • Challenges in the manufacturing of DPI systems
  • Future trends in inhaled drug delivery
  • 14:10 RPL554, a novel "first-in-class" inhaled drug for the treatment of exacerbations of chronic obstructive pulmonary disease (COPD), and cystic fibrosis

    Jan-Anders Karlsson

    Jan-Anders Karlsson, CEO , Verona Pharma

  • Treatment and prevention of COPD exacerbations
  • Severe exacerbations of COPD and hospital re-admissions shortly after discharge
  • RPL554 – a novel dual PDE3 and PDE4 inhibitor with bronchodilator and anti-inflammatory effect
  • 14:50 Afternoon Tea

    15:20 PANEL DISCUSSION: Are children over-diagnosed and trivialised?

    16:00 Chairman’s Closing Remarks and Close of Day One

    Ewan Walters

    Ewan Walters, Medical Director, Teva UK Ltd

    8:30 Registration & Coffee

    9:00 Chairman's Opening Remarks

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK

    9:10 Design implications and challenges in developing treatments for idiopathic pulmonary fibrosis

    Andy Kenwright

    Andy Kenwright, Project Statistician , Roche Products Limited

  •  Background to current state of play in treating IPF
  • Clinical development challenges in IPF
  • Combination therapy – is it the future ?
  • 9:50 A pivotal role for the alarmin IL-33 during respiratory exacerbations

    Matthew  Robinson

    Matthew Robinson, Senior Scientist, MedImmune

  • The alarmin IL-33 is increased in the lungs of COPD patients
  • IL-33 exacerbates lung inflammation in a mouse model of smoke and virus challenge
  • IL-33 function is attenuated over time by oxidation
  • 10:30 Morning Coffee

    11:00 Clinical development of "generic" DPls

    Katerina Athanassiou

    Katerina Athanassiou, CR Director, ELPEN Pharmaceutical Co. Inc

  • EMA regulations about the clinical development of OIP
  • Regulatory obstacles on the development
  •  Is the term “generic” applicable to DPIs?
  • 11:40 Scientific aspects of quality regulations in respiratory drug development

    Stefan Leiner

    Stefan Leiner, Chemical-Pharmaceutical Expert, Boehringer Ingelheim

  • What are the current philosophical differences between US and EU quality regulations for inhalation products?
  • How do they translate into current hot topics, e.g. generic approval
  • What would be quality requirements for future therapies (lung cancer, sustained release)?
  • 12:20 Networking Lunch

    13:30 Improving inhealed therapies

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK

  • Improving adherence
  • Improving drug delivery by inhaler and formulation performance
  • Improving pharmacology with new molecules and combination
  • 14:10 Performance Characterisation of Inhalation Products

    Jan Olof Svensson

    Jan Olof Svensson, Principle Scientist AstraZeneca R&D, AstraZeneca

  • Performance characterization in general
  • In-vivo relevant testing
  • Different types of delivery systems - different challenges
  • 14:50 Afternoon Tea

    15:20 Comparison of generic OIP experiences in different markets

    Michelle Lee-Bourner

    Michelle Lee-Bourner, Head of Regulatory, Mylan Pharma UK

  • An overview of the regulatory requirements for key markets globally
  • Market preferences and payer pressures
  • The key scientific challenges in the key markets.
  • Is one global development program ever likely to be possible?
  • 16:00 Corticosteroid insensitivity in severe asthma: Mechanisms and new targets

    Pankaj Bhavsar

    Pankaj Bhavsar, Research Lecturer, Imperial College London

  • Relative corticosteroid  (CS) insensitivity is displayed in both inflammatory and structural cells of patients with severe asthma compared to non-severe asthma
  • Decreased glucocorticoid receptor (GR) expression with impaired nuclear translocation in airway smooth muscle cells (ASMC), associated with reduced dexamethasone-mediated attenuation of p65 recruitment to gene promoters, may underlie the mechanism of CS insensitivity in severe asthma
  • Therapies to overcome corticoid insensitivity could be targeted at improving nuclear translocation of GR in ASMC of severe asthma patients; p38 MAPK inhibitors also provide a potential new therapy for the treatment.
  • 16:40 Chairman’s Closing Remarks and Close of Day Two

    Peter Daley Yates

    Peter Daley Yates, Director Clinical Pharmacology, GSK


    Sponsors and Exhibitors

    Official Publication


    Preliminary list of attendees


    Sponsors and Exhibitors


    Sponsors and Exhibitors

    Fidelta is highly qualified to conduct and support projects in discovery and early pre-clinical development. We offer a complete integrated drug discovery capability of medicinal chemistry, pharmacology and ADME/PK and have extensive experience in taking projects through the Hit to Lead and Lead Optimisation phases. With a strong emphasis on translational science we focus on patient derived and disease-relevant test models/systems. Our pharmacology portfolio includes design and execution of in vitro studies on human primary cells and disease tissue samples as well as ex vivo analyses for biomarker selection. Comprenhensive animal models of asthma, COPD and pulmonary fibrosis complement our extensive expertise in the respiratory area. Entrust us with your research project to gain high quality results.

    Media Partners

    International Journal of Biomedical Engineering and Technology

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    IJBET addresses cutting-edge research in the multi-disciplinary area of biomedical engineering and technology. Medical science incorporates scientific/technological advances combining to produce more accurate diagnoses, effective treatments with fewer side effects, and improved ability to prevent disease and provide superior-quality healthcare. A key field here is biomedical engineering/technology, offering a synthesis of physical, chemical, mathematical and computational sciences combined with engineering principles to enhance R&D in biology, medicine, behaviour, and health. IJBET includes the Asia-Pacific Chapter in Biomedical Wireless Technology (APC-BWT).

    International Journal of Medical Engineering and Informatics

    Official Publication

    IJMEI promotes an understanding of the structural/functional aspects of disease mechanisms and the application of technology towards the treatment/management of such diseases. It seeks to promote interdisciplinary collaboration between those interested in the theoretical and clinical aspects of medicine and to foster the application of computers and mathematics to problems arising from medical sciences. IJMEI includes authoritative review papers, the reporting of original research, and evaluation reports of new/existing techniques and devices. Each issue also contains a comprehensive information service.

    International Journal of Technology, Policy and Management

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    IJTPM is a refereed international journal that provides a professional and scholarly forum in the emerging field of decision making and problem solving in the integrated area of technology policy and management at the operational, organisational and public policy levels.

    International Journal of Biotechnology

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    IJBT provides an international forum and refereed authoritative source of information in the field of Biotechnology and Biotechnics, with emphasis on management and economics, as well as the political and social issues. It aims to disseminate knowledge, provide a learned reference in the field, and establish channels of communication between academic and research experts, policy makers and executives in industry, commerce and investment institutions.

    International Journal of Healthcare Technology and Management

    Official Publication

    IJHTM is a series emerging from the International Journal of Technology Management. It provides an international forum and refereed authoritative sources of information in the fields of the economics and management of technology in healthcare.

    International Journal of Medical Engineering and Informatics

    Official Publication

    IJMEI promotes an understanding of the structural/functional aspects of disease mechanisms and the application of technology towards the treatment/management of such diseases. It seeks to promote interdisciplinary collaboration between those interested in the theoretical and clinical aspects of medicine and to foster the application of computers and mathematics to problems arising from medical sciences. IJMEI includes authoritative review papers, the reporting of original research, and evaluation reports of new/existing techniques and devices. Each issue also contains a comprehensive information service.

    Media Partners



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    International Pharmaceutical Industry


    IPI gives you an insight into all areas of Biopharm, Medical, Pharmaceutical and Healthcare. IPI provides a proven supportive means of communication to the Pharmaceutical, Bio Pharmaceutical, Nutraceutical and Medical Devices industry, incorporating the latest in research and technology innovations, regulatory guidelines, marketing and communication strategies.

    Pharmaceutical Manufacturing and Packing Sourcer


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    In the November issue: a review of green issues in the pharmaceutical supply chain, and the lowdown on the latest in temperature-controlled packaging and distribution. To find out more and subscribe, visit http://www.samedanltd.com/magazine/15



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    Bentham Science


    Bentham Science Publishers is a major STM journal publisher of 130 plus print and online journal. Out of these, 40 journals have already registered good IMPACT FACTORS as per Journal Citation Reports® 2017. These titles have extensive readership mostly in Europe and North America. For a detailed profile please visit our website at http://www.benthamscience.com. Besides, Bentham Science publishes eBooks in all areas of Science, Technology and Medicine. Our eBooks provide professionals, academicians, corporate researchers, graduates and undergraduates worldwide with the most current information in their subject areas of interest. Our eBooks are also available in the ePub and Kindle formats besides the PDF edition here http://ebooks.benthamscience.com/. Bentham is offering attendees of this conference discounts on its publication. For more information click here



    PharmaVision offers a consultancy service providing independent pharmaceutical thematic research to the healthcare industry, the investment community and competitive intelligence specialists. We perform due diligence research and provide expert commentary in healthcare. Our reports combine scientific analysis in drug delivery, R&D technologies and pharmaceutical products including patient modelling, product/technology forecasts and market trends evaluation.



    MedNous is a print publication and website about medical innovation in Europe. It carries exclusive interviews with companies that are at the forefront of medical technology, as well as contributor articles from prominent practitioners. Our mission is to identify significant advances in medicine and to explain how this innovation is being commercialised. In doing so, we talk to venture capitalists about what products and platforms they are supporting. We report on how regulators cope with the accelerating pace of innovation. And we regularly cover the latest developments in the discovery and development of new medical concepts in the area of antibodies, vaccines, small molecules, regenerative medicine and nanomedicines. MedNous combines the English word for medicine with the Greek word for intellect. And those with nous are readers of our publication. Visit our website: www.mednous.com

    Medical News Today


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    Drug Development Technology


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    Innovations in Pharmaceutical Technology (IPT)


    Innovations in Pharmaceutical Technology (IPT) magazine offers in-depth comment and analysis written by experts from within the field. IPT covers the latest developments in drug discovery, laboratory technology, formulation, delivery systems, and other insights and innovations in the field. The magazine also presents sector-specific events, company and individual profiles, and reviews. IPT is a platform for those involved in pharmaceuticals and biotechnology to share their ideas with other key industry figures.

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    Crowd Reviews


    CrowdReviews.com is a transparent online platform for determining which products and services are the best based on the opinion of the crowd. The crowd consists of Internet users which have experienced products and services first-hand and have an interest in letting other potential buyers their thoughts on their experience.

    Antibodies Online


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    Swiss Biotech Association


    The Swiss Biotech Association (SBA) is the national industry association for biotechnology, including pharmaceuticals, diagnostics, agriculture, food, cosmetics, environmental biotechnology, and specialty chemicals. Members are companies active in modern biotechnology, such as R&D, Production, Marketing and Sales, Finance, Services and Consulting. SBA provides a networking platform for Life Science clusters, academic and federal institutions the like. Founded in March 1998, the Association grows steadily.

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    Drug Discovery World


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    Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by experts in their respective fields and cover all aspects of drug discovery from genomic and proteomic approaches, computational drug design, medicinal chemistry and the translation of these sciences to therapies.

    COPD: Journal of Chronic Obstructive Pulmonary Disease


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    ONdrugDelivery Magazine


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    Contract Biotechnology


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    Drug Target Review


    Drug Target Review’s quarterly magazine, website and annual events program provides high quality content with peer-written articles that are submitted exclusively by the world’s most respected scientists in their field. This attracts a committed base of readers, users and delegates made up of senior decision-makers from the life science and drug discovery industries at the top pharmaceutical companies, as well as academics and scientists from the top research institutes across the globe.



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    British Pharmacological Society


    The British Pharmacological Society (BPS) is the primary UK learned society concerned with research into drugs and the way they work. Our members work in academia, industry, regulatory agencies and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects. Clinical pharmacology is the medical speciality dedicated to promoting safe and effective use of medicines for patient benefit. Clinical pharmacologists work as consultants in the NHS and many hold prominent positions in UK Universities.



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    speaker image






    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.


    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.


    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.


    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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