The recognition of pain as a disease, not a symptom, is an important part of patient understanding, but it also has an impact the drug discovery and development process. There are many different ways that patients present with the disease and a common understanding of the pathology driving the different disease states is important. In the workshop, we will discuss how findings in humans on disease chronification and biomarkers can guide and aid the development of new drugs for pain.

•Better understanding of the pain patient throughout drug development
•Understanding what human pain biomarkers teach us about the pain disease
•Seeing the impact of understanding sensitisation/chronification in treating pain
•What can be learned from descending control

Previous attendees include:

Afferent Pharmaceuticals, Inc.; Alder BioPharmaceuticals, Inc; Arachos Pharma; Array BioPharma; Asahi Kasei; Bayer HealthCare Pharmaceuticals; BCN Peptides S.A.; Centre for Human Drug Research; Convergence Pharmaceuticals; Deventer Ziekenhuis; Dr Paul Kornan; Eli Lilly; Eli Lilly And Company; Eli Lily Damark A / S; GlaxoSmithKline; Gr³nenthal; HPR Human Pharmacodynamic Research GmbH; Imperial College London; Janssen Pharmaceutica Inc; Levicept; Merck & Co.; Mochida Pharmaceuticals; Mundipharma International; Mundipharma Research GmbH & Co. KG; Neuroscience Technologies; Novartis; Orion Pharma UK; Pennsylvania Hospital; Pfizer; Pfizer Group; PRA Health Sciences; PRA Health Services; PRA International; Rambam Medical Center; The Lewisham Hospital N H S Trust; Thomson Reuters; Tools4patient; UCL; University of Manchester;

Workshop LEADER


Karin Hygge Blakeman

Medical Scientific Liason, Grunenthal

Dr Hygge Blakeman has worked in the pain field for almost two decades, with more than 10 of those years in the pharmaceutical industry. Starting in preclinical discovery, moving to translational science into the medical sciences, Karin brings experience from the many different steps of a drug’s way to the market.

Dr Hygge Blakeman received her Ph.D. in Neurophysiology from the Karolinska Institute in 2002 for studies on spinal mechanisms of pain. She moved on to do a post doc with AstraZeneca and then joined them to lead a team focused on pre-clinical models of analgesia and in vivo pharmacology. In 2010, she joined a team of preclinical and clinical scientists to form the Translational Sciences Department, were she was responsible for analgesia biomarkers in project stages from idea to clinical trials. Since 2015 she is a part of the medical department at Grunenthal Nordics, focusing on introducing new pain treatments to physicians.


The Grünenthal Group is an independent, family-owned, international research-based pharmaceutical company headquartered in Aachen, Germany. We are an entrepreneurial specialist delivering true benefits to patients. By sustainably investing in research and development above the industrial average, we are committing to innovation in order to treat unmet medical needs and bring value-adding products to markets.

Workshop programme

13:30 Registration

14:00 Opening remarks and introductions

14:10 Why is treating pain as a disease important?

14:50 The impact of sensitisation and chronification

15:30 Coffee

16:00 The role of descending inhibition

16:40 Nocimarkers- Human biomarkers for pain conditions

17:20 Closing remarks

17:30 End of workshop


Holiday Inn Kensington Forum

97 Cromwell Road
London SW7 4DN
United Kingdom

Holiday Inn Kensington Forum

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 



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CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.


There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.


Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.


Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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