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Oligonucleotide therapeutics - the emerging medicine class - are harnessing the therapeutic benefit of targeting genetic material via antisense, mRNA, RNAi, saRNA and siRNA. Their market growth: CAGR of 13.7% projected to reach USD 8.2 billion by 2024 is driven by their potential to provide more efficacious and less toxic alternatives to small molecules. They bring about the ability to affect targets that have been considered “non-draggable”. Heavy investments in oligonucleotide therapeutic discovery have created an emerging market need for drug delivery technologies.
 

SMi’s inaugural Oligonucleotide Therapeutics and Delivery conference is here to keep you updated. By bringing together leading representatives of pharmaceutical, biotechnology and academic institutions, the 2-day conference will provide first-hand information on the latest clinical trial candidates and a platform for exchanging ideas for tackling the biggest challenge: DELIVERY. From optimizing particle size to choosing the right nanocarrier systems, the conference will address delivery to non-hepatocyte cells such as cancerous tissues and overview the most successful platforms. Discussions will be centered around improving targeted therapy uniting the field’s biggest players to share their opinions.
 

Established on the success of our RNA Therapeutics series, we look forward to welcoming you at Oligonucleotide Therapeutics and Delivery to join the conversation around maximizing the potential of oligo-based treatments.

  • Gain first-hand insight into oligonucleotide therapy clinical success up to date for improving development of novel agents in your pipeline 
  • Listen to case studies presenting the latest candidates undergoing pre-clinical and clinical research 
  • Deepen your understanding of crucial delivery methods and available platforms for non-hepatocytic delivery   
  • Collaborate with members of the oligonucleotide community leading pharmaceutical, biotechnology and academic representatives to maximise future opportunities
  • RNA Biology/Discovery
  • Novel Therapeutic Modalities
  • Innovation Technologies
  • C-level Scientific Executives
  • Formulation and Drug Delivery
  • Clinical Research and Development
  • Cell Biology

 

Accanis Therapeutics; Advanced Cell Diagnostics – A Bio-Techne Brand; Aescap 2.0; Alnylam Pharmaceuticals UK & Ireland; AmpTec GmbH; Aseptic Technologies SA; AstraZeneca; Bachem AG; BianoGMP; BioNTech IMFS GmbH; BioNTech RNA Pharmaceuticals; Boehringer Ingelheim Pharma GmbH & Co. KG; Calithera Biosciences; CEPI - Coalition for Epimemic Prepardness Innovation; Chemgenes Corporation; Curevac Ag; Dicerna Therapeutics.; Duke University School of Medicine; Ethris GmbH; Exicure Inc.; F.Hoffmann-La Roche AG; GSK; Horizon Discovery; InteRNA Technologies BV; Intertek; Lipocalyx; MedImmune; MHRA; MiNA Therapeutics; N4 Pharma UK Limited; New England Biolabs; NHS Blood and Transplant Authority; Nitto Avecia; NOF Europe GmbH; Nouscom SRL; ProQR Therapeutics; RCSI; RCSI Royal College of Surgeons in Ireland,; RNA Medco; ROCHE; Roche Diagnostics Deutschland GmbH; Roche Innovation Center; Russell Publishing Ltd; Sanofi; Sanofi-Aventis Deutschland GmbH; Takeda Development Centre Europe Ltd.; TCR Solutions; The Italian Institute of Technology; The RNA Medicines Company; Thermo Fisher Scientific; University Medicine Mainz Hospital; University Of Portsmouth; University Of Surrey; Yuria Pharma;
 

Conference programme

8:30 Registration & Coffee

9:00 Chair's Opening Remarks

Nagy Habib

Nagy Habib, Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
View Bio

9:10 Small activating RNAs – a novel therapeutic class of oligonucleotides

Matthew Catley

Matthew Catley, Research Director, MiNa Therapeutics Ltd
View Bio

• Description of saRNA technology to upregulate transcription and broad applicability to a range of therapeutic targets
• Generation of a lead candidate saRNA to HNF4a for liver disease
• Update on MiNA’s lead saRNA clinical agent MTL-CEBPA – Clinical PD and efficacy

9:50 Targeted Delivery of C/EBPa-saRNA by RNA Aptamers

Nagy Habib

Nagy Habib, Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
View Bio

• Understanding the principles of RNA activation and possibilities of therapeutic benefit
• Harnessing small activating RNAs for the treatment of Pancreatic ductal adenocarcinoma
• Evaluating aptamers and appropriate means of targeted delivery
• Looking at lessons learnt from using saRNA for oncological purposes

10:30 Morning Coffee

11:00 Clinical development of AsiDNA, a first in class decoy agonist oligonucleotide targeting DNA damage response in tumor cells

Wael Jdey

Wael Jdey, Head of Biology, Onxeo S.A.

• Introduction to platON™: proprietary chemistry platform based on a library of decoy agonist oligonucleotides which generates disruptive compounds acting on intracellular DNA-binding targets
• Introduction to AsiDNA the leading decoy agonist generated from platON and targeting DNA damage response function
• Recent preclinical highlights: AsiDNA abrogates resistance to multiple anti-cancer targeted therapies
• Recent clinical development of AsiDNA
• Outlining next steps of clinical development

11:40 Oligonucleotides as a therapeutic option for Duchenne Muscular Dystrophy (DMD)

Andre  Muller-York

Andre Muller-York, Senior Medical Affairs Director, Sarepta Therapeutics Germany GmbH

• Background for the oligonucleotides PMOs / PPMOs and the MoA for RNA-exon skipping
• I.v. PMOs / PPMOs for RNA-exon skipping in DMD
• Clinical results for the PMOs / PPMOs from the Sarepta pipeline in DMD

12:20 Networking Lunch

13:20 Case study: Discovery and development of RNA-therapeutics for Triple Negative Breast Cancer

Maria Luisa Pineda

Maria Luisa Pineda, CEO and Co-founder, Envisagenics
View Bio

• Envisagenics’ SpliceCore platform integrates proprietary machine learning algorithms, high performance computing, and RNA-splicing analytics to identify disease-specific alternatively spliced RNA that will function as therapeutic targets
• Discovery of TNBC specific splicing isoforms
• Design and development of RNA-therapeutics targeting TNBC specific splicing isoforms using machine learning
• Functional qualification of SpliceCore designed ASOs

14:00 Introduction of non-chiral phosphorodithioates into Locked Nucleic Acids

Meiling LI

Meiling LI, Senior Scientist , F. Hoffmann-La Roche Ltd.
View Bio

• RNA therapeutics have clearly demonstrated their medical benefit.
• Phosphorothioates have been extensively profiled and cover most of the clinically investigated entities.The complexity of diastereoisomers have resulted in the great challenges in understanding PK/PD of stereomixed oligonucleotides.
• Introduction of non-chiral phosphorodithioates dramatically reduces the diastereomeric complexity and can potentially improve PK/PD of oligonucleotides.
• Combinations of phosphorodithioates and stereodefined motives will allow to rapidly identify highly potent one single phosphorothioate LNA isomer, which is supported by recent in vitro and in vivo data.

14:40 Fluorescent Base Analogs (FBAs) in Gapmer Technology: Stealth Labeling of Antisense

Tom Baladi

Tom Baladi, Postdoctoral Research Fellow, AstraZeneca
View Bio

• Outline of the design and assets of FBAs: modifying nucleobases to gain fluorescence properties without using external dyes
• Synthesis of FBAs and incorporation into ASOs using the phosphoramidite chemistry
• Assessment of structural, biological and photophysical properties of the modified ASOs
• Derivatization utilizing different FBAs and impact on uptake and imageability

15:20 Afternoon Tea

15:50 Oligonucleotide DP development and manufacturing for orphan ophthalmic diseases

Vera Brinks

Vera Brinks, Director Pharmaceutics, ProQR Therapeutics
View Bio

• An overview of oligonucleotide products in development at ProQR Therapeutics for (ultra) orphan ophthalmic diseases
• Outlining the DP development challenges related to intravitreal (IVT) administered products
• Assessment and implementation of terminal sterilization of oligonucleotide products in development at ProQR Therapeutics

16:30 Formulation strategies for the development of injectable Spiegelmer drug product solutions

Stefan Vonhoff

Stefan Vonhoff, VP Chemistry&Manufacturing, NOXXON Pharma AG
View Bio

• Introducing the Spiegelmer technology approach and NOXXON’s clinical development program
• Defining a target product profile for injectable Spiegelmer drug product solutions
• Overcoming development challenges for Spiegelmers drug product solutions
• Establishing quality control methods for Spiegelmer drug product manufacturing and release in

17:10 Chair’s Closing Remarks and Close of Day One

Nagy Habib

Nagy Habib, Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
View Bio

8:30 Registration & Coffee

9:00 Chair's Opening Remarks

Nagy Habib

Nagy Habib, Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
View Bio

9:10 The Nucleic Acid Therapy Accelerator (NATA): a new UK research initiative to accelerate the potential of nucleic acid medicines

Mark Edbrooke

Mark Edbrooke, Industrial Advisor , Nucleic Acid Therapy Accelerator
View Bio

• As part of the UK’s Life Sciences Industrial Strategy, the Medical Research Council (MRC) founded an innovative new UK lab-based research initiative, the NATA
• NATA is addressing the key challenges faced in the development of nucleic acid medicines including the high cost of manufacture, improved cellular targeting, and to increase safety
• NATA is working in partnership with industry, academia and medical charities
• NATA will be based at the Harwell Science and Innovation Campus, at the heart of a growing HealthTec Cluster

9:50 Delivery of Novel siRNA constructs for treating cancer

David Evans

David Evans, Chief Scientific Officer, Sirnaomics, Inc
View Bio

• Creating siRNA payloads for cancer treatment
• Understanding the challenges of cell-specific delivery: how to get size and efficacy right?
• Choosing the appropriate delivery system
• Presenting success and future steps

10:30 Morning Coffee

11:00 Recent clinical progress with RNAi loaded KRAS-LODER for pancreatic tumour

Amotz Shemi

Amotz Shemi, CEO, Silenseed

• Introducing the RNAi loaded KRAS-LODER for targeting KRAS mutations
• Overviewing recent clinical success in phase II trials
• Presenting phase II clinical trials results including primary and secondary endpoints
• Outlining next steps of programme

11:40 INT-1B3 (miR-193a-3p mimic): from bench-to-bedside

Michel Janicot

Michel Janicot, CDO, InteRNA Technologies BV

• Focus on microRNA R&D
• Success (bench-to-bedside) story for Oncology therapeutic intervention
• Preclinical to first in human study transition

12:20 Networking Lunch

13:20 Self-deliverable RNAi ex-vivo and in-vivo

Alexey Wolfson

Alexey Wolfson, CEO, Advirna

• Exploring the sdRNAi technology and its use for RNA interference
• How can siRNAs be modified to achieve self-delivery?
• Discussing what is required for the efficient delivery of RNAi into all cell types ex-vivo and to certain organs in vivo
• Which cell types can self-deliverable RNAis target?

14:00 Immunochemotherapeutic oligonucleotides for cancer treatment

Steve Pascolo

Steve Pascolo, Founder and CEO, Miescher Pharma GmbH
View Bio

• Introducing the immunochemotherapeutic oligonucleotide approach
• Highlighting success in oncology mouse models to date
• Addressing challenges of delivery and maximising the EPR effect
• Discussing next steps of the program and evaluating potential delivery solutions

14:40 Afternoon Tea

15:10 The tool-box approach to improve the performance of siRNA-platform technology

Adrien Weingartner

Adrien Weingartner, Principal Scientist, Group Leader Drug Delivery, Silence Therapeutics AG

• Interplay of design and function
• Stability and duration of action
• Linker design and valency of ligands
• Is there room for additional improvements?

15:50 Oligonucleotide conjugates for delivery to the CNS

Suzan Hammond

Suzan Hammond, Research Assistant, University Of Oxford
View Bio

• Cell penetrating peptides and antibodies are two delivery vehicles capable of direct conjugation to phosphorodiamidate morpholino oligonucleotides (PMOs).
• PMOs are charged neutral oligonucleotides able to alter RNA metabolism through steric blockage mechanisms. For many neuromuscular diseases, spinal muscular atrophy, Duchenne muscular dystrophy and myotonic dystrophy, PMOs are therapeutically effective.
• Cell penetrating peptides (CPPs) have been developed for systemic delivery of PMOs in difficult to penetrate tissues; skeletal muscle and CNS.
• An arginine rich CPP with hydrophobic core has been previously shown to penetrate the spinal cord tissue in vivo following systemic administrations.
• Further modification to arginine rich CPPs reduce kidney injury marker (KIM1) while maintaining activity
• More recently, an antibody engineered to bind to transferrin receptor (Anti-TfR-PMO) of the BBB was tested in vivo and shown to yield high levels of brain penetration.
• I will discuss the latest designs of CPPs and antibodies used for CNS delivery of PMO.

16:30 Chair’s Closing Remarks and Close of Day Two

Nagy Habib

Nagy Habib, Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
View Bio

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FEATURED SPEAKERS

Adrien Weingartner

Adrien Weingartner

Principal Scientist, Group Leader Drug Delivery, Silence Therapeutics AG
Amotz Shemi

Amotz Shemi

CEO, Silenseed
Andre  Muller-York

Andre Muller-York

Senior Medical Affairs Director, Sarepta Therapeutics Germany GmbH
Maria Luisa Pineda

Maria Luisa Pineda

CEO and Co-founder, Envisagenics
Meiling LI

Meiling LI

Senior Scientist , F. Hoffmann-La Roche Ltd.
Nagy Habib

Nagy Habib

Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
Stefan Vonhoff

Stefan Vonhoff

VP Chemistry&Manufacturing, NOXXON Pharma AG
Suzan Hammond

Suzan Hammond

Research Assistant, University Of Oxford
Tom Baladi

Tom Baladi

Postdoctoral Research Fellow, AstraZeneca
Wael Jdey

Wael Jdey

Head of Biology, Onxeo S.A.

Adrien Weingartner

Principal Scientist, Group Leader Drug Delivery, Silence Therapeutics AG
Adrien Weingartner

Alexey Wolfson

CEO, Advirna
Alexey Wolfson

Amotz Shemi

CEO, Silenseed
Amotz Shemi

Andre Muller-York

Senior Medical Affairs Director, Sarepta Therapeutics Germany GmbH
Andre  Muller-York

David Evans

Chief Scientific Officer, Sirnaomics, Inc
David Evans

Dr. Evans obtained his BSc and PhD from Imperial College, London. Over the last 3 decades he has built scientific research teams focused on target validation, drug discovery and high throughput screening of small molecule and siRNA libraries to identify lead candidates for development in Oncology and other indications. David has more than 15 years’ experience in the RNAi field – building genome scale screening capabilities for target identification in Oncology and other indications at TGEN and Dharmacon prior to cofounding Sirnaomics to focus on developing siRNA as a therapeutic. David previously worked at the Frederick National Lab for Cancer Research and in the Boston area with Millennium Pharmaceuticals and Serono Pharmaceuticals.

Maria Luisa Pineda

CEO and Co-founder, Envisagenics
Maria Luisa Pineda

Dr. Maria Luisa Pineda is the co-founder and CEO of Envisagenics, Inc. a biotech spinout of Cold Spring Harbor Laboratory that integrates proprietary machine learning algorithms, high performance computing, and RNA-splicing analytics to identify disease-specific splicing variants as therapeutic targets. Envisagenics has leveraged its SpliceCore® software platform for therapeutic development with its first pipeline of assets in triple negative breast cancer. Dr. Pineda received her PhD from the prestigious Watson School of Biological Sciences at Cold Spring Harbor Laboratory, then she acquired investment experience in technology and life-science startup companies at Canrock Ventures and Golden Seeds, LLC. Under Dr. Pineda’s leadership, Envisagenics has acquired nearly $2.5M in funding from the National Institutes of Health Small Business Innovation Research (SBIR) program and pre-seed investments from Topspin Partners and the Long Island Emerging Technology Fund, and from Breakout Labs, a Peter Thiel foundation. Envisagenics has raised over $5M from investors including Third Kind Venture Capital (3KVC), Cosine, LLC (NYC biotech investors), Dolby Family Ventures, Dynamk Capital, Madrona Venture Group, M12, NY Empire State Development (ESD), and SV Angel. Envisagenics has won several prestigious competitions such as the JLABS Artificial Intelligence for Drug Discovery QuickFire Challenge and was named the North American Winner of the Innovate.AI competition. More recently, Dr. Pineda secured Envisagenics’ first oncology partnership with a large pharmaceutical company. Dr. Pineda was named one of the top 20 Latinas in NYC by El Diario, NYC’s oldest Spanish Language newspaper and is an alumna of the Stanford Latino Entrepreneur Leaders Program developed by the Latino Business Action Network and the Stanford Graduate School of Business.

Mark Edbrooke

Industrial Advisor , Nucleic Acid Therapy Accelerator
Mark Edbrooke

Mark Edbrooke is an Independent Scientific Consultant specialising in oligonucleotide therapeutics and macromolecule delivery. He worked for 20 years in GSK where he ran a transnational functional genomics department, and latterly a Discovery Performance Unit (DPU) focused on the development of therapeutic siRNAs and antisense oligonucleotides. He then joined AstraZeneca (AZ) to work on therapeutic antisense, microRNA, and modified RNA. He now consults for numerous UK-based universities, as well as for the NATA, a government-funded accelerator for nucleic acid therapeutics.

Matthew Catley

Research Director, MiNa Therapeutics Ltd
Matthew Catley

Dr Matthew Catley completed his PhD studies of airway signalling pathways involved in lung disease with Peter Barnes at Imperial college. He completed further post-doctoral studies on the pharmacology of inhaled therapeutics with Maria Belvisi at Imperial College. Moving to UCB/Celltech he worked on monoclonal antibodies for the treatment of autoimmune and inflammatory disorders. In 2012 he moved to AstraZeneca in Gothenburg to help establish and run the preclinical bioscience department. After a year at Covance, Matthew Joined MiNA therapeutics in 2019 as Research Director. Matthew has developed a range of therapeutic modalities including small molecules, antibodies, peptides and oligonucleotides.

Meiling LI

Senior Scientist , F. Hoffmann-La Roche Ltd.
Meiling LI

Dr. Meiling Li is currently working as a senior scientist in RNA therapeutics in Hoffmann La Roche, Basel, Switzerland. Her research focuses on the modifications of the backbones in terms of stereodefined phosphorothioates, phosphorodithioates and other highly interested modifications. Dr. Li received her PhD from University of Oxford (UK) in organic synthetic chemistry. She then worked at ETH Zurich as a postdoc on nucleoside chemistry. In 2017 she moved to Hoffmann La Roche as a scientist in RNA therapeutics research department. Dr. Li has been involved in different projects of drug development and contributed greatly to the understanding of structure activity relationship (SAR) of oligonucleotide drugs.

Michel Janicot

Chief Development Officer, InteRNA Technologies BV
Michel Janicot

Nagy Habib

Professor of Surgery, Imperial College, Co-founder MiNA therapeutics, Imperial College London
Nagy Habib

Nagy Habib is a leading translational researcher on liver cancer and its treatment. He pioneered the first clinical trial in the use of adenovirus and plasmid for the treatment of liver cancer, as well as the use of plasmid gene therapy in hydrodynamic gene delivery. He is the first person in the West to publish a clinical trial on the use of adult bone marrow derived stem cells for the treatment of patients with liver insufficiency.

He has published on the evolution of molecular biology of tumours from oncogene, tumour suppressor gene, epigenetic modification, gene therapy, stem cell therapy, RNA (Ribonucleic acid) and saRNA (small activating RNA) and RNA aptamers.

He is the inventor of, and was co-author of the first publication about the use for radiofrequency in devices used in liver surgery (Habib™ 4X), as well as interventional endoscopy (Habib™ EndoHPB – HPB: Hepatopancreatobiliary) and interventional radiology (Habib™ Percutaneous HPB, Habib™ VesCoag, Habib™ VesOpen).

Nagy is currently Lead Clinician and Head of the Department of HPB Surgery at Imperial College London. In June 2007 he was also appointed Pro Rector for Commercial Affairs at the university. He holds a gold award from the Advisory Committee for Clinical Excellence, which is given in recognition of exceptional contributions from NHS consultants, and he was named as one of Britain’s top surgeons in December 2011 by the Saturday Times Magazine. In December 2012, he was awarded the TAKREEM AWARD for Science and Technology for scientific work in liver cancer and the technological development of the Habib 4X surgical device. In 2015, Nagy was awarded a Foreign Membership of the prestigious French Académie Nationale de Chirurgie.
 

Stefan Vonhoff

VP Chemistry&Manufacturing, NOXXON Pharma AG
Stefan Vonhoff

Stefan Vonhoff, Ph.D. is VP Chemistry&Manufacturing at NOXXON Pharma AG, Berlin, Germany, a biotech company developing Spiegelmers – enantiomeric aptamers – for various therapeutic indications in the oncology area.
Stefan holds a Ph.D. in chemistry from University College London and received post-doctoral training in the Department of Chemistry at the ETH Zurich. He joined NOXXON in 1999 to establish the manufacturing process for L-nucleoside phosphoramidites and pegylated L-RNA aptamers. Today, his main responsibility is to coordinate external manufacturing and QC/QP-release activities for starting materials, drug substance, parenteral drug product and clinical trial supply.
 

Steve Pascolo

Founder and CEO, Miescher Pharma GmbH
Steve Pascolo

Trained as an immunologist at the Pasteur Institute (Paris, France), I used mouse models to test and develop mRNA-based vaccines (direct injection of mRNA) during my post-doc in Tuebingen, Germany. In 1999, I co-founded CureVac with Dr. Hoerr and Dr. von der Mulbe. I was CSO of the company from 2000 till 2006, developing the technology, implementing the worldwide first GMP production of mRNA and performing the worldwide first clinical studies where humans got injections of in vitro transcribed mRNA. In 2006 I joined the oncology department of the University Hospital of Zurich, Switzerland and continued the development of immunotherapies based on RNA. In 2008 I founded Miescher Pharma to support this work. In 2017, we implemented in Zurich an mRNA platform https://www.cancer.uzh.ch/en/Research/mRNA-Platform.html. In collaboration with several research and clinical departments in Zurich we test different mRNAs capable to enhance immunity against cancer. In addition, we developed modified RNA oligonucleotides to perform immunochemotherapies.

Suzan Hammond

Research Assistant, University Of Oxford
Suzan Hammond

Suzan Hammond, PhD, is a career research scientist with experience focused on neuromuscular genetic disorders. Dr Hammond received her degree from Northwestern University studying in vivo modelling for the neurodegenerative disease spinal muscular atrophy. As a research scientist at the University of Oxford, Suzan focuses on patient unmet needs by developing delivery vehicles for antisense oligonucleotides towards the brain, spinal cord and skeletal muscle. She works with academic and industrial collaborators to advance her work to early clinical development. Dr Hammond’s work has been featured on the Naked Scientist Podcast and Zone in with Zon for trending nucleic acid research.

Tom Baladi

Postdoctoral Research Fellow, AstraZeneca
Tom Baladi

Tom Baladi was awarded his Ph.D. in Medicinal Chemistry in 2016 following his work on the design and development of selective small molecule kinase inhibitors at the Paris-Saclay University. For his second post-doctoral fellowship, he joined in 2018 the Wilhelmsson research group at Chalmers University (Gothenburg, Sweden) as part of the FoRmulaEx platform, a Swedish industry/academia consortium. He now focuses on the synthesis of fluorescent nucleobase analogs and their incorporation into various nucleotide-based modalities for in vitro imaging, to enable studies of drug-delivery systems. His work is performed at AstraZeneca Gothenburg, another active member of FoRmulaEx.

Vera Brinks

Director Pharmaceutics, ProQR Therapeutics
Vera Brinks

Vera Brinks is director pharmaceutics at ProQR Therapeutics, Leiden, the Netherlands. With her team she is responsible for early and late phase oligonucleotide DP development. Vera received her PhD in 2009 in the field of biopharmaceutics at the Leiden University (The Netherlands). Before joining ProQR 6 years ago, Vera has worked as postdoctoral fellow at the FDA (CDER, DTP), and as postdoctoral researcher at the Utrecht University (the Netherlands) for 6 years. She has over 25 publications in the field of therapeutic proteins, biosimilars and formulation-related quality attributes.

Wael Jdey

Head of Biology, Onxeo S.A.
Wael Jdey

Exhibitors

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VENUE

Venue To Be Confirmed

London, United Kingdom

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Speaker Interview - Maria Luisa Pineda, Envisagenics

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RNA infographic

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P-328 RNA Past Atendee list (P-311)

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David Blakey - MiNA therapeutics, Past presentation

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Christopher Bunker- Bio-techne, Past presentation

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Heinrich Haas - BioNTech, Past presentation

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Surender Vashist - AstraZeneca, Past presentation

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Ethris, Past presentation

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Dr Simon Newman - NanoGenics, Past presentation

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Davis C. Henchall - Future neuro, Past presentation

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Dr Kirsty Wydenbach - MHRA, Past presentation

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David Deutsch - MHRA, Past presentation

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Bo Rode Hansen - GENEVANT, Past presenation

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Dr. Michel Janicot - InteRNA Technologies, Past presentation

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Brochure 2020

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Short Programme

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Full programme

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Exhibitors


ChemGenes

Exhibitors
http://www.chemgenes.com

ChemGenes, an ISO 9001 certified company established in 1981, is the industry leader in manufacturing oligonucleotide synthesis reagents and has consistently provided the highest quality phosphoramidites and solid supports in the market. Our facility, just outside of Boston/Cambridge Massachusetts USA, is setup for bulk manufacturing of therapeutic grade phosphoramidite and solid support DNA/RNA synthesis products for GMP grade oligonucleotide manufacturing. Additionally, ChemGenes carries the widest variety of modified phosphoramidites and supports currently used in oligonucleotide synthesis including Microarray Technology, Oligonucleotide Therapeutics, Oligonucleotide Based Probes and other areas of Nucleic Acid research. ChemGenes remains devoted to providing you with invaluable customer service and comprehensive technical support.


Tosoh Bioscience

Exhibitors
https://www.tosohbioscience.com/

Tosoh Bioscience is an acknowledged global leader in liquid chromatography with a focus on bioseparations. Our team of chromatography experts enables our biopharma partners to provide safe and efficient therapies against life threatening diseases. Our portfolio encompasses SEC instruments and a comprehensive line of media and process development, HPLC, and UHPLC columns. The products are used in R & D, process development, downstream processing, and quality control of biologics, biosimilars or biobetters. Typical applications comprise the purification of therapeutic proteins and oligonucleotides at lab, pilot, and commercial scale, as well as their characterization and QC analysis by (U)HPLC. Tosoh Bioscience is part of the Tosoh Group, a Japanese chemical and specialty products group with over 100 companies worldwide and a workforce of about 13000 people.

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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