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The alarming increase of resistance against multiple currently available antimicrobial agents is leading to a rapid loss of treatment options against infectious diseases. Antimicrobial resistance is partially due to a misuse or abuse of anti-infective drugs- a strategy to overcome this is the optimization of the antimicrobial dosing regimens. Inappropriate drug choice and suboptimal dosing are two major factors contributing to the emergence of drug resistance and consequently, poorer clinical outcomes.

This workshop explores the three pharmacodyamic properties of antibiotics that best describe killing activity: time-dependence, concentration-dependence, and persistent effects. The aim of the workshop is to demonstrate that class-appropriate PK/PD parameters are excellent predictors of antibiotic efficacy.
 

1. Understand the categorisation of antibiotics according to their pharmacodynamic properties

2. Explore how the pattern of activity affects the goal of the antibiotic therapy

3. Learn how to predict ideal dosing regimens for different classes of antibiotics

4. Discover how class-appropriate PK/PD parameters are excellent predictors of antibiotic efficacy
 

Workshop programme

13:30 Registration and coffee

14:00 Opening Remarks and Introductions

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
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14:10 Patterns of Activity

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
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• A: Concentration-dependent killing and prolonged persistent effects
• B: Time-dependent killing and minimal persistent effects
• C: Time-dependent killing and moderate to prolonged persistent effects.
 

14:50 Goal of Therapy

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
View Bio

• Maximize concentrations – aim: Peak/MIC
• Maximize duration of exposure – aim: T>MIC
• Maximize amount of drug – aim: 24h-AUC/MIC
 

15:30 Afternoon Tea

15:50 The PK/PD relationship

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
View Bio

• PK dosing proves that one dose is not appropriate for all patients
• Pharmacodynamics prove that one target level is not appropriate for all patients
 

16:30 Q&A Session

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
View Bio

17:00 Chairman’s Closing Remarks and Close of Day One

William  Hope

William Hope , Professor of Therapeutics and Infectious Diseases, University Of Liverpool
View Bio

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FEATURED SPEAKERS

William  Hope

William Hope

Professor of Therapeutics and Infectious Diseases, University Of Liverpool

William Hope

Professor of Therapeutics and Infectious Diseases, University Of Liverpool
William  Hope

William Hope (BMBS, FRACP, FRCPA, PhD), is Professor of Therapeutics and Infectious Diseases at the University of Liverpool in the UK. Professor Hope is a Fellow of the Royal Australasian College of Physicians and a Fellow of the Royal College of Pathologists of Australasia. Professor Hope qualified in Medicine in 1991, before undertaking specialist training in infectious diseases and clinical microbiology. He completed his PhD in antimicrobial pharmacology in 2006, while undertaking fellowships at the University of Manchester, UK, and the National Institutes of Health, Bethesda, USA. He was an NIHR Clinician Scientist and this award focused on individualised antimicrobial therapy. Professor Hope leads the newly formed Centre for Antimicrobial Pharmacodynamics, which provides the pharmacodynamic packages for new antibiotics. Areas of special interest and research are antimicrobial pharmacokinetics and pharmacodynamics, antimicrobial drug development and individualisation of antimicrobial therapy. He is a Fellow of the American Academy of Microbiology and European Society of Clinical Microbiology and Infectious Diseases.
 

VENUE

Holiday Inn Kensington Forum

97 Cromwell Road , London, United Kingdom

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

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Holiday Inn Kensington Forum

97 Cromwell Road
London SW7 4DN
United Kingdom

Holiday Inn Kensington Forum

Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

HOTEL BOOKING FORM

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WHAT IS CPD?

CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

CPD AND PROFESSIONAL INSTITUTES

There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

As a formal provider of CPD certified activities, SMI Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

GLOBAL CPD

Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

CPD Certificates

We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@smi-online.co.uk

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